Scientist - Medicinal Chemistry

Req ID:  207631

Saffron Walden, GB, CB10 1XL Harlow, GB, CM19 5TR

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Scientist - Medicinal Chemistry


Are you a BSc graduate with a chemistry discipline?


Have you got the desire to join a company who play a part in improving health and lives?


Do you have a passion for drug development?



Based at our site in Saffron Walden or Harlow, you will be working as part of a team of enthusiastic medicinal chemists designing and synthesising novel compounds with the ultimate goal being to identify a potential candidate suitable for drug development.



What you'll be doing


  • Contribute to the design of routes, plan and efficiently perform the synthesis of target compounds.

  • Work closely with colleagues in multidisciplinary teams to deliver results for your clients.

  • Communicate clearly and effectively with key stakeholders, interfacing directly with clients.

  • Find solutions to technical problems using the scientific literature. 

  • Use a variety of modern synthetic techniques (microwave technology, parallel synthesis, photo- and electrochemistry).

  • Use modern purification techniques (automated column chromatography and HPLC). 

  • Gain experience in medicinal chemistry and develop an understanding of project biological data.

  • Learn about the drug discovery process as part of a fast-moving and dynamic contract research organization. 

  • Be willing to expand your non-lab skills within areas such as presentation, scientific writing and operational or continuous improvement initiatives.


What we offer you


  • Industry recognised training and development opportunities.

  • Clear career progression and performance based pay.

  • A very highly regarded and comprehensive benefits package from day one, including bonus!

  • Real and regular opportunities to grow your medicinal chemistry knowledge.


Skills and qualifications


  • An effective communicator and team player.

  • To have good attention to detail, organisational and time management skills.

  • To have a dynamic, can-do attitude and a flexible approach to problem solving.

  • A desire to develop a career discovering new medicines for the future.

  • BSc / MSc qualified (minimum 2.1) within a chemistry related discipline

  • A commitment to personal development to enable future career progression.

  • A passion for practical synthetic chemistry.

  • Identify synthetic chemistry problems and work with colleagues to implement solutions.

  • To be able to interpret NMR and mass spectrometry data.

  • To be able to use scientific literature and provide solutions to technical problems.


About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. 


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.


At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.