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Senior Scientist - Separation Science

Req ID:  44284

Saffron Walden, CAM, GB, CB10 1XL

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Scientist Analytical

Charles River is seeking an exceptional, ambitious, innovative and highly motivated lab-based Senior Scientist to work in our Separation Sciences team at our Saffron Walden site, purifying a diverse range of Medicinal Chemistry small molecules in order to advance drug discovery projects for our clients. 

We are seeking a Senior Separations Scientist who has significant industrial experience with a degree or PhD level qualification and a passion for applying scientific expertise to drug discovery collaborations. Adept in working as part of a multi-disciplinary team, you will need to possess the flexibility required to work in a goal-oriented environment, as well as:


  • A strong scientific and practical background in automated purification services / UPLC/HPLC/ SFC/ Mass spectrometry instrumentation, with hands on approach to fault finding and generation of high quality data. Knowledge of MassLynx, Chemstation, Chromscope and/or Trilution would be advantageous.
  • Ability to work well under pressure, independently and to tight deadlines.
  • Dynamic workload prioritisation, problem solving, clear communication and multitasking.
  • Identifying and implementing new technologies and creative approaches to increase effectiveness, engaging support and promoting at a department level.
  • Enthusiastic approach to mentoring of junior team members-providing scientific input to guide purification experiments and data interpretation.
  • To operate in a safe manner at all times and to comply with CRL site-based guidelines
  • To work within the framework of the Charles River core values of Collaborate, Lead, Own, Care


About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2018.