Associate Research Leader Medicinal Chemistry

Req ID:  207655

Saffron Walden, GB, CB10 1XL Harlow, GB, CM19 5TR

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

The Role


Are you an experienced medicinal chemist ready to take on their first people leader role?


Do you want to join a global contract research organisation that helps improve lives?


Have you got a strong commitment to personal development, and to be a scientific ambassador in our business?


Charles River Discovery are excited to be recruiting for an Associate Research Leader in Medicinal Chemistry, to provide scientific leadership within the chemistry team at our drug discovery facilities in Cambridge, UK.


You will be an experienced medicinal chemist, who is able to provide scientific leadership to enable the delivery of high quality medicinal and synthetic chemistry, from target validation through to clinical candidate nomination in partnership with our clients.


The Associate Research Leader will be instrumental in contributing to high-performing, collaborative, inter-disciplinary teams and will be an experienced drug discovery scientist with a keen interest in cutting edge science and a proven track record of advancing compounds towards the clinic. 



What You'll be Doing


  • Provide independent medicinal chemistry leadership on one or more project teams, by supporting the design and co-ordination of work plans and using creative problem solving to achieve project goals.

  • Offer drug discovery expertise, both internally and to clients, challenging thinking and using own initiative to help to influence, define and deliver scientific objectives for self and others.

  • Independently interrogate data generated for the project and use this data to influence strategy of defined scientific area.

  • Design and implement efficient synthetic routes to target compounds using literature searching tools, keeping up to date with modern synthetic methodology.

  • Collaborate effectively with colleagues in multidisciplinary teams.

  • Communicate clearly and effectively with key stakeholders, interfacing directly with clients.

  • May be responsible for managing discipline resources and finances within project within an acceptable budget.

  • May contribute to Business Development proposals and face-to-face meetings as a discipline Lead.

  • Contribute to securing new business opportunities, working as a discipline lead to prepare scientific proposals and present to potential new clients.


What We Offer You


  • A very comprehensive salary and benefits package from day one, including a large pension contribution, private medical, private dental, critical illness cover, bonus and more!

  • The opportunity to gain more industry training and experience.

  • The chance to work with state of the art equipment, in well resourced laboratories.

  • Leadership and management training, and continued professional development.

  • Global opportunities and strong career progression.

  • To be able make a difference to health and well being of people.

  • Flexible working options.


Skills and Qualifications


  • PhD qualified within a chemistry related discipline or BSc / MSc qualified within a chemistry related discipline with strong and proven experience in a lab-based environment.

  • Proven experience in a CRO / biotech / pharma setting. 

  • Extensive experience in in synthetic and medicinal chemistry including significant contributions to drug design supporting H2L and/or LO transitions and delivery of publications and/or co-inventorship on patent applications.

  • Experience of interacting closely across disciplines and influencing medicinal chemistry strategy within projects.

  • Broad medicinal chemistry expertise covering different therapeutic areas and project phases across multiple target classes.

  • Excellent interpersonal, communication and presentation skills with the ability to mentor others.

  • Good attention to detail, organisational and time management skills.

  • A dynamic, can-do attitude and a flexible approach to problem solving. Sound scientific judgement which has impacted on the direction and delivery of projects or departmental initiatives.

  • The ability to act proactively and make decisions for self and others.


About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. 


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.


At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.