For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.
Are you looking for a varied job in an international working team? Bringing your knowledge and expertise together with other experts to come to a tailored support to our client needs?
Within the Section of Regulatory Toxicology in the Regulatory Affairs Department, we are looking for a new colleague:
Senior Regulatory Toxicologist
About the department:
Our regulatory affairs support is characterized by a tailored, case-by-case approach, depending on specific client needs. We provide full registration dossier services, but also consultancy on the right testing strategy, hazard and risk assessment, support with submission or communication with regulatory authorities and other stakeholders.
In addition, our regulatory affairs services also involve support with the preparation of expert statements/opinions, weights of evidence and study waivers fit for regulatory submission, and writing of manuscripts for publication in scientific journals.
About the team:
Our international working team provides regulatory support for our global chemical, agrochemical, biocidal and pharmaceutical clients.
Our subject-matter experts guide clients in their registration process and support interactions with regulatory authorities with the goal to bring new products to the market while ensuring their safe use and efficacy.
About your roll:
As Senior Regulatory Toxicologist you will apply your knowledge on toxicology and human toxicological risk assessment within at least one legislative framework (i.e. pharmaceuticals/non-clinical safety, medical devices; agrochemicals, biocides and/or industrial chemicals) at a challenging level for you, while being part of an enthusiastic team. We want you to do what you are good at and want you to develop further, while sharing your knowledge and expertise to the benefit of our clients and your colleagues.
Your activities may include, depending on your interests, knowledge and experience:
• Evaluation and assessment of all aspects of human toxicological data;
• Compilation of toxicology sections in dossiers for different legal frameworks (i.e. non-clinical parts of the dossier for pharmaceuticals; agrochemicals; biocides; industrial chemicals);
• Preparation of expert statements; literature searches; advice on testing strategy and data gap analysis;
• Use of in silico methods/NAMs for the assessment of various toxicological endpoints;
• Assessment of endocrine disrupting properties within EFSA/ECHA framework;
• Internal peer review and supervision of junior colleagues;
• Coordination of complex regulatory projects;
• Working closely together with your own regulatory team members, CRL study directors, sales and client services team, as well as staying in contact with clients and authorities;
• Presenting at (inter)national conferences and participating in internal and/or external working groups.
Job Qualifications
Your Profile:
• Relevant academic training, focusing on toxicology, biology, life sciences and/or (bio)chemistry; ERT registration is a pre;
• High level of knowledge of at least one legal framework mentioned above (preferably non-clinical safety of pharmaceuticals);
• At least 5 years of experience in the field of regulatory toxicology; the ability to work independently and to peer review and supervise junior colleagues;
• Experience in at least one of the following topics will be considered as a strong benefit: knowledge and experience with the use of in silico methods (e.g. LHASA Nexus package, OECD QSAR Toolbox; VEGA; Toxtree etc.); knowledge and experience with non-clinical (safety) testing and ICH guidelines; knowledge and experience with impurity qualification in pharmaceutical drug products; knowledge and experience with the assessment of endocrine disrupting properties under ECHA/EFSA framework; high level of expertise in a particular toxicological field (e.g. pharmacology; ADME; genotoxicity; reproductive and developmental toxicity; neurotoxicity; carcinogenicity);
• Experience in dealing with Competent Authorities is a pre;
• A basic background in chemistry is a pre;
• You are a team player with a pro-active, self-learning, result oriented, enthusiastic, flexible, dynamic and critical attitude.
Our offer:
• We offer a position for 32-40 hours per week in an open culture and informal atmosphere
• Working from home is allowed. Also foreign candidates from other EU countries are encouraged to apply;
• Working hours can be determined in consultation, so that an optimal work-life balance is possible.
Depending on your location, country-specific benefits may apply on our excellent primary and secondary terms of employment.
About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.
About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.
At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.
Helping you find your moment
You take great care and effort when you apply for a job with us. Rest assured that we’ll be just as diligent in finding the role that’s right for you. Here’s how our hiring process works:
Job Search
Learn about CRL, our culture, and why we do the work we do while also searching for roles that match your interests and expertise.
Application
Create a profile and apply to as many roles as you have an interest.
Note: Depending on the role, you may be required to include a resume in your application.
Assessment and application review
Complete assessments, if requested, to determine whether the role is likely to be a good fit for you – and vice versa. The recruiter will review your resume and qualifications against the requirements of the role and will determine next steps.
Note: At any point in the process, you can log into your profile to review the status of your application.
Interview
Engage in our interview process by meeting with a group of interviewers who will provide information on the company, culture, and your role while also asking you questions to assess your skills, interests, and expertise. This is also a great time for you to ask questions and better understand how we foster a sense of belonging at Charles River.
Note: Charles River leverages technical and behavioral-based interview questions based on our DNA (Care, Lead, Own, and Collaborate). Please familiarize yourself with the DNA and be prepared to relate your experiences to them.
Job offer and onboarding
Receive a competitive offer either by phone or email from a Charles River recruiter or hiring manager. The offer will include your title, salary, location, and other relevant information.
Note: Upon acceptance, you will work with your recruiter to confirm a start date and will receive paperwork to electronically complete prior to your start. For US-based roles, upon your acceptance, you will be required to take a pre-employment drug screen and pass a criminal background check.
Job Search
Learn about CRL, our culture, and why we do the work we do while also searching for roles that match your interests and expertise.
Application
Create a profile and apply to as many roles as you have an interest. Note: Depending on the role, you may be required to include a resume in your application.
Assessment and Application Review
Complete assessments, if requested, to determine whether the role is likely to be a good fit for you – and vice versa. The recruiter will review your resume and qualifications against the requirements of the role and will determine next steps.
Note: At any point in the process, you can log into your profile to review the status of your application.
Interview
Engage in our interview process by meeting with a group of interviewers who will provide information on the company, culture, and your role while also asking you questions to assess your skills, interests, and expertise. This is also a great time for you to ask questions and better understand how we foster a sense of belonging at Charles River. Note: Charles River leverages technical and behavioral-based interview questions based on our DNA (Care, Lead, Own, and Collaborate). Please familiarize yourself with the DNA and be prepared to relate your experiences to them.
Job offer and onboarding
Receive a competitive offer either by phone or email from a Charles River recruiter or hiring manager. The offer will include your title, salary, location, and other relevant information. Note: Upon acceptance, you will work with your recruiter to confirm a start date and will receive paperwork to electronically complete prior to your start. For US-based roles, upon your acceptance, you will be required to take a pre-employment drug screen and pass a criminal background check.
Featured jobs
Important things are happening every moment at Charles River. This means exciting new career opportunities for you to explore. Take a look and apply today!
Looking for something else? Search all jobs.
Moment by moment
At Charles River, you’ll be able to contribute to incredible breakthroughs while experiencing exciting opportunities for growth and development.
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UX/UI Designer
Advocate for user-centered design solutions. Create distinctive, consistent, branded digital experiences across multiple platforms, devices, and channels.
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Senior UX/UI Designer
Define and drive UX/UI strategies and interaction designs – from scratch and for scale – that solve business and user problems.
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Associate Director
Work with Senior UX/IX Designers and developers to assess problems and develop solutions. Execute on plan by building coding standardizations and automating processes.
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Director, Digital Data Enablement
Lead UX management and operational teams across business units and technical teams. Identify and define fit-for-purpose strategies to integrate best practices.
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Senior Director UX/UI Design
Mentor, coach, and guide designer teams on design strategy related to research insights, execution, continuous integration, and automated deployment.
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Animal Care Technician I - V
Maintain the well-being of our animals by providing food, water, and a clean environment.
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Animal Care Technologist I - V
Provide specialized care to maintain and monitor our animals’ health and physical environment.
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Veterinary Technician
Help monitor, document, and triage all laboratory animal health cases.
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Team Leader / Supervisor
Supervise, train, mobilize, empower, and develop a high-performing team.
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Research Associate
Coordinate and plan activities according to study plan guidelines.
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Intern Level I
Support process/procedure improvement based on site and department needs. Gain knowledge of our corporate environment to navigate cross-functional department collaboration.
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Intern Level II
Complete comprehensive departmental projects incorporating mentorship of Level I interns as a professional development component.
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Biomanufacturing Technician I-III
Oversee the production, formulation, and banking of cellular products while maintaining compliance with GMP, GDP, and aseptic guidelines.
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Biomanufacturing Lead / Specialist
Maintain in-depth knowledge of specialized equipment to address questions as a Subject Matter Expert for the required equipment.
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Clinical Veterinarian I-III
Responsible for delivering professional veterinary services and helping to manage all phases of health care for the animal colony.
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Senior Clinical Veterinarian
Utilize knowledge of laboratory animal medicine to optimize the scientific objectives of animal research protocols.
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Principal Veterinarian / Associate Director
Conduct veterinary consults, make treatment recommendations, communicate with study directors, and follow cases through resolution.
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Director, Laboratory Animal Medicine
Provide technical and professional oversight of all animal care and use functions involving site laboratory animals.
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Technician I-III
Follow SOP and protocols in the areas of animal handling, husbandry, and blood/urine collection.
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Technician IV-V
Handle advanced technician duties, including anesthesia, leadership and specialized sample collections.
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Project Leader (Scientific)
Serve as a scientific expert for the Lab with responsibility for staff-conducted studies.
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Team Leader (People Leader)
Oversee team activities and gain leadership skills on the path to becoming a Team Supervisor.
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Team Supervisor (People Leader)
Responsible for overall employee supervision, staff development, and team success.
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Financial Analyst I
Help analyze financial data, extract/define relevant information, and interpret data.
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Financial Analyst II
Responsible for analysis, forecasting, budgeting, accounting administration, and reporting of projects.
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Senior Financial Analyst
Handle weekly and monthly forecasting and annual budget preparation. Prepare financials and key indicators for business reviews.
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Manager, Business Finance
Partner with operating businesses to raise standards in key decision areas. Present a dynamic industry, competitor, and economic context.
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Finance Director, Operations
Support all business aspects, working with site teams to direct weekly/monthly forecasting and annual budget preparation.
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Biomanufacturing Technician I
Support the production, formulation, and banking of novel cellular products (including cGMP, GDP, and aseptic processing).
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Biomanufacturing Technician II
Perform specialized activities in the production, formulation, and banking of novel cellular products (including cGMP, GDP, and aseptic processing). Train Biomanufacturing Technician 1.
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Biomanufacturing Technician III
Help advance the production, formulation, and banking of novel cellular products (including cGMP, GDP, and aseptic processing) while interacting with clients.
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Biomanufacturing Lead / Specialist
Maintain in-depth knowledge of specialized equipment to address questions as a Subject Matter Expert for the required equipment.
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Biomanufacturing Supervisor
Oversee biomanufacturing personnel, ensuring compliance with cGMP’s, CRL quality systems, and process documents in biomanufacturing.
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Biomanufacturing Manager
Lead biomanufacturing activities in the start-up and cGMP production of novel cellular products. Schedule and manage staff, ensuring a safe and compliant working environment.
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Client Manager
Ensures high-quality customer service through multi-site coordination. Deliver timely, accurate, and comprehensive responses to sponsor requests.
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Business Development Director
Deliver profitable sales growth by targeting and visiting clients to build strong relationships and customer loyalty.
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Senior Business Development Director
Plan and execute a territory-based field sales strategy. Drive growth through targeted long- and short-term account plans.
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Regional Sales Manager
Manage sales team within North America's Safety Assessment sales region to achieve sales and profit goals.
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Director
Partner with site leadership to achieve performance goals, develop staff, and deliver succession planning.
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Senior Director / General Manager
Lead a multi-functional team to ensure integrated operations. Collaborate with senior leadership to form plans, objectives, and policies.
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Executive Director
Lead a global, multidisciplinary team. Develop short and long-term strategic plans to maximize growth and profitability.
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Corporate Vice President
Provide leadership, direction, and advice to leadership and finance teams. Accountable for financial planning, directing, and controlling.
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About Charles River
Charles River is an early-stage Contract Research Organization (CRO). Here, we are passionate about our role in improving the quality of people’s lives. With 100 sites around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our clients’ unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies, hospitals, and academic institutions around the world.
Supporting your well-being
Your dedication and passion make a life-saving difference in lives around the world. We’re committed to providing you with benefits that elevate your quality of life.
Financial
- Earnings + incentives
- Retirement benefits
- Vacation + time away
- Recognition
- Employee assistance fund
Career
- Professional development opportunities
- Career development
- Awards
- Educational support
Health and wellness coverage
- Employee well-being support
- Family support programs
- Parental benefits + family formation benefits
- Work-life balance flexibility
Social and Community
- Culture of belonging
- 11 employee resource groups (ERGs) with >4,000 members, where all employees are welcome
- Opportunities for paid volunteer time off
- Community outreach + matching gift + engagement activities
About Charles River
Charles River is an early-stage Contract Research Organization (CRO). Here, we are passionate about our role in improving the quality of people’s lives. With 100 sites around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our clients’ unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies, hospitals, and academic institutions around the world.