For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.
The Role
Can you independently run a range of immunological assays and develop new assays to support our invitro capabilities?
Have you got immunological experience in Immuno-oncology, autoimmune disease and inflammation (inc. neuroinflammation), infection or microbiome programs?
Do you want to join a global CRO committed to improving health?
Our waterside site down in Portishead, Bristol has an opportunity for an additional Senior Scientist to join their in vitro biology team.
You’ll be working independently under strategic guidance with understanding and application of scientific and technical standards, principles, theories, concepts, and techniques in a predominantly lab-based environment.
What You'll be Doing
- Independently run a wide range of immunological assays using techniques such as flow cytometry, IncuCyte, MACS sorting, culture and differentiation of primary cells and cell lines, ELISA, Luminex, TR-FRET, and ex-vivo tissue processing.
- Implement available assays and develop new immunological assays to support the in vitro biology capabilities in the areas of immuno-oncology, autoimmune disease and inflammation (inc. neuroinflammation), infection or microbiome programs.
- Interrogate own and others data to generate reports where conclusions/future directions are scientifically sound and provide technical and scientific leadership to drive project progression.
- Guide, coach and mentor junior scientific staff, helping to train on specific techniques and provide technical knowledge, where needed.
- Project lead or deputy-Project lead or execute IVB studies with minimal supervision from the Project lead.
- Leverage BD/CS and operational team to introduce novel work for the site, including scoping calls with client and revision of scientific project proposals.
Skills and Experience
- MSc within a relevant discipline .PhD desirable.
- Demonstrable lab-based experience in disciplines of immuno-oncology, autoimmune disease and inflammation (inc. neuroinflammation).
- Awareness of Health and Safety standards within the labs and ability to work safely within this environment.
- Excellent communication skills, able to relay scientific information accurately.
- Strong passion for working within drug discovery, able to keep abreast of industry updates and share amongst peer groups.
- Strong problem solving and communication skills, with ability to work collaboratively within a team.
- Proficient in IT – Microsoft, Outlook, and Teams.
- Clear understanding and grasp of the drug discovery process.
Nice to have:
- Previous industry experience in the labs, ideally from pharma /CRO / biotech.
- Some demonstrable project leadership skills, with ability to liaise effectively with internal and external stakeholders.
- Experience of working in a multidisciplinary unit on integrated drug discovery projects.
- Demonstrable practical skills in executing biological assays in a pharma/biotech/CRO environment.
What We offer You:
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A very comprehensive benefits package from day one, including a generous pension contribution, and flexible health benefits.
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Access to great discounts via our CREDS discount scheme.
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Global opportunities and strong career progression.
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The chance to work on several varied projects and liaise globally and nationally with other business areas.
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To be able make a difference to health and wellbeing of people.
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To continue your own career growth.
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Parental leave.
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Group Life Assurance and Group Income Protection.
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Remote GP access 24/7.
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Well being support and initiatives.
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Cycle to work scheme.
About DiscoveryDiscovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.
About Charles RiverCharles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.
At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.
Helping you find your moment
You take great care and effort when you apply for a job with us. Rest assured that we’ll be just as diligent in finding the role that’s right for you. Here’s how our hiring process works:
Job Search
Learn about CRL, our culture, and why we do the work we do while also searching for roles that match your interests and expertise.
Application
Create a profile and apply to as many roles as you have an interest.
Note: Depending on the role, you may be required to include a resume in your application.
Assessment and application review
Complete assessments, if requested, to determine whether the role is likely to be a good fit for you – and vice versa. The recruiter will review your resume and qualifications against the requirements of the role and will determine next steps.
Note: At any point in the process, you can log into your profile to review the status of your application.
Interview
Engage in our interview process by meeting with a group of interviewers who will provide information on the company, culture, and your role while also asking you questions to assess your skills, interests, and expertise. This is also a great time for you to ask questions and better understand how we foster a sense of belonging at Charles River.
Note: Charles River leverages technical and behavioral-based interview questions based on our DNA (Care, Lead, Own, and Collaborate). Please familiarize yourself with the DNA and be prepared to relate your experiences to them.
Job offer and onboarding
Receive a competitive offer either by phone or email from a Charles River recruiter or hiring manager. The offer will include your title, salary, location, and other relevant information.
Note: Upon acceptance, you will work with your recruiter to confirm a start date and will receive paperwork to electronically complete prior to your start. For US-based roles, upon your acceptance, you will be required to take a pre-employment drug screen and pass a criminal background check.
Job Search
Learn about CRL, our culture, and why we do the work we do while also searching for roles that match your interests and expertise.
Application
Create a profile and apply to as many roles as you have an interest. Note: Depending on the role, you may be required to include a resume in your application.
Featured jobs
Important things are happening every moment at Charles River. This means exciting new career opportunities for you to explore. Take a look and apply today!
Looking for something else? Search all jobs.
Moment by moment
At Charles River, you’ll be able to contribute to incredible breakthroughs while experiencing exciting opportunities for growth and development.
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Technician I-III
Follow SOP and protocols in the areas of animal handling, husbandry, and blood/urine collection.
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Technician IV-V
Handle advanced technician duties, including anesthesia, leadership and specialized sample collections.
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Project Leader (Scientific)
Serve as a scientific expert for the Lab with responsibility for staff-conducted studies.
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Team Leader (People Leader)
Oversee team activities and gain leadership skills on the path to becoming a Team Supervisor.
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Team Supervisor (People Leader)
Responsible for overall employee supervision, staff development, and team success.
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About Charles River
Charles River is an early-stage Contract Research Organization (CRO). Here, we are passionate about our role in improving the quality of people’s lives. With 100 sites around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our clients’ unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies, hospitals, and academic institutions around the world.
Supporting your well-being
Your dedication and passion make a life-saving difference in lives around the world. We’re committed to providing you with benefits that elevate your quality of life.
Financial
- Earnings + incentives
- Retirement benefits
- Vacation + time away
- Recognition
- Employee assistance fund
Career
- Professional development opportunities
- Career development
- Awards
- Educational support
About Charles River
Charles River is an early-stage Contract Research Organization (CRO). Here, we are passionate about our role in improving the quality of people’s lives. With 100 sites around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our clients’ unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies, hospitals, and academic institutions around the world.