Mass Spectrometry Laboratory Manager

Req ID #:  80132

Worcester, MA, US, 01608

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

We are seeking a Mass Spectrometry Laboratory Manager for our Discovery site located Worcester.


The Mass Spec Lab Manager is responsible for oversight of the mass spec laboratories.  These duties include coordination and scheduling of maintenance of HPLC and mass spec instrumentation, organization and equipping of the mass spec laboratories, space utilization, and maintenance of the spare parts inventory.  The Mass Spec Labs Manager will assist with troubleshooting instrumentation and software issue be the lead trainer for the LC/MS/MS systems, and assist in the evaluation of new instrumentation.  


The following are responsibilities related to the Mass Spectrometry Laboratory Manager:


  • Oversee LC/MS/MS metrology:
    • Schedule and coordinate equipment maintenance
    • Point of contact for LC/MS/MS service
    • Ability to troubleshoot instrumentation problems
    • Ability to correct minor instrumentation issues
    • Maintain all calibration and maintenance records
    • Assist with the organization and equipping of the Mass Spec Laboratories including spare parts
    • Perform IQ/OQ/PQ testing on assigned instrumentation; Oversee in-house equipment maintenance for assigned instrumentation
  • LC/MS/MS Configuration / Software Management
    • Ability to install and configure MS and HPLC software
    • Interface with IT to configure acquisition computers 
    • Manage the software upgrade process
  • LC/MS/MS Training
  • Evaluate new mass spectrometric and chromatographic equipment and techniques
  • Assist with scheduling coordination in the mass spec labs
  • Interact independently with internal and external contacts
  • Lead or coordinate mass spec lab training initiatives and process improvement efforts
  • Mentor, assist, and train LC/MS/MS users
  • Follow company SOPs, BOPs, Policies, and Practices


The following are minimum qualifications related to the Mass Spectrometry Laboratory Manager position:


Education:  Bachelor’s degree (B.A. /B.S.) or equivalent in Life Sciences, Computer Science or related discipline.  
Experience:  Minimum 7 years of working with and/or administering and supporting LC/MS applications. Strong understanding of drug discovery or related life science industry experience is required. 
An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
Certification/Licensure:  None
Other:  In-depth knowledge of HPLC and mass spec instrumentation and software. Proficiency in MS Office and LIMS. This position requires a strong attention to detail and the ability to work independently with minimal direction to meet multiple, simultaneous, time-sensitive deadlines. Excellent communication and interpersonal skills including the ability to deliver informative, well-organized presentations. Ability to work well in a team environment. Familiarity with Sciex mass spectrometers and Agilent, Waters, and Shimadzu HPLCs is a plus.



About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 320 patents and 74 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.


Equal Employment Opportunity


<span style="font-family:"Arial",sans-serif">Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet.


<span style="font-family:"Arial",sans-serif">If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to <span style="font-family:"Arial",sans-serif"><span style="font-family:"Arial",sans-serif">. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications<span style="font-family:"Arial",sans-serif">.


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