Share this Job

Director Pharmacology

Req ID #:  32341

Worcester, MA, US, 01650

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work e perform. In return, we’ll help you build a career that you can feel passionate about.



We are seeking an experienced Director Pharmacology for our Discovery site located in Worcester, MA.


We are seeking a highly motivated and enthusiastic Pharmacology leader who enjoys working with an exceptional team  The successful individual in this role will organize day to day activities including the design, execution and evaluation of preclinical studies.You will plan and execute biochemical, in vitro and in vivo studies through collaboration with senior staff and sponsors. You will also be reponsible for facilitating staff scientific growth through education/training, quality initiatives & new model investigation/establishment.


The following are minimum requirements related to the Director Pharmacology position:


  • Education: Doctoral degree (Ph.D., D.V.M or M.D.) or equivalent in biochemistry, molecular biology, pharmacology or related area.
  • Experience:  10 or more years post doctoral experience in cancer research; minimum 5 years experience in the pharma industry.  Preferred: previous oncology and cancer drug discovery and development experience; project or department leadership of an industry-based oncology drug discovery or development program.
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • Other:  Experience in cancer drug development, tumor biology, biochemistry, pharmacology and quality assurance experience. Proven expertise in cancer research and drug discovery/development. Demonstrated successful project management experience. Experience in the biomarker area and published results in peer-reviewed journals preferred. Strong knowledge and working experience in various biochemical and molecular biology techniques, including Elisa assay, protein purification, antibody production,   molecular hybridization, Western blots, etc. Effective communication skills (verbal and written). Strong analytical, organizational and management skills. Knowledge of cancer research; target identification, target modulation and/or biomarkers. Documented track record in carrying out independent research. Strong knowledge of statistical principles and statistical skills. Proficient in operation, troubleshooting, and routine maintenance of analytical instruments and data system. Strong research experience in molecular mechanisms and molecular biology techniques. Familiar with FDA regulatory and AAALAC-related issues. Able to manage multiple tasks and priorities for successful project completion.    


About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 320 patents and 74 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 11,000 employees within 70 facilities in 18 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges.  Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2016, revenue increased by 23.3% to $1.68 billion from $1.36 billion in 2015.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~70% of the drugs approved by the FDA in 2016.

For more information, please visit

Equal Employment Opportunity
Charles River Laboratories, Inc. is an Equal Opportunity Employer M/F/Disabled/Vet

Job Segment: Manager, Biochemistry, Biotech, Pharmaceutical, Management, Science, Research