Senior Scientist, Bioinformatics

Req ID #:  201517

South San Francisco, CA, US, 94080

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

The individual in this position will be member of the senior scientific leadership staff of the group.  The position requires outstanding competencies of bioinformatics within and outside the field of application. The individual has demonstrated deep understanding of scientific and technical principles, theories, concepts and techniques. Conceptualizes and develops new methods and procedures with help of scientific literature. Demonstrates strategic influence to expedite defined scientific area. Defines own scientific objectives aligned to project goals and suggests new ideas or initiatives.


Essential Duties and Responsibilities



  • Develop, perform and troubleshoot bioinformatics data processing and analysis across phage antibody discovery campaigns using NGS and Sanger sequencing, 
  • Design and QC phage antibody libraries for primary lead discovery, and optimization of existing leads. Interact with research clients regularly to explain hypothesis and analyses
  • As a member of the site leadership team contribute to all research plans. 
  • Will manage a small team.
  • Function as the primary contact for the planning related to bioinformatics analysis and method development. 
  • Recognizes and provides, using clear scientific rationale, solutions to a variety of technical problems of increasing scope and complexity within projects and client facing.
  • Prepare and present out of scope data analysis reports and communicate insights internally and externally.
  • Perform oversight of bioinformatics scientists and mentor junior staff in areas such as experimental design, workflows and processing procedures.
  • Perform troubleshooting on data processing and analysis tasks within and outside standard project scopes.
  • Continuously review scientific literature in the field and outside to scout new technologies and scientific advances. Conceptualize, design and implement with help of junior staff.
  • Attend and present at international scientific meetings.
  • Perform all other related duties as assigned

Job Qualifications





•Education: Master’s degree (MS/M) in relevant field with adequate experience.  PhD degree in bioinformatics or a scientific related discipline is preferred. 
•Experience: Minimum of 8 years of related experience in contract research, academic or pharmaceutical industry. Minimum of 6 years of field related bioinformatics experience. 

“The pay range for this position is $160,000-$180,000 . Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.”

About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 320 patents and 74 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. 


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.


Equal Employment Opportunity

Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.


If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.


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Nearest Major Market: San Francisco
Nearest Secondary Market: Oakland

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