Scientist, Research & Development

Req ID #:  195111
Location: 

Northridge, CA, US, 91325

For over 40 years, HemaCare, a Charles River company, has worked to making a positive impact on the world by providing the highest quality cellular material and services to biotech and pharmaceutical companies and research organizations that are performing innovative research and developing novel cell-based therapies.


We recognize that our success depends on the vision and passion of our employees; that is why we are devoted to making HemaCare a rewarding and valuable place to work. We believe in making a difference, and at HemaCare, you will make a difference every day.


IMPORTANT:   In order to be considered for this position, a resume/CV must be uploaded and submitted during the application process.  Please make sure work history and education are added correctly.  

Job Summary

The Scientist, R&D will work under the guidance of the Scientific Director to develop new processes, conduct research to meet strategic marketing initiatives and further the growth and development of Cell Solutions.

 

Essential Responsibilities:
•    Evaluate and provide technical guidance on new processes for cell isolation, enrichment, and analysis.  
•    Research, develop and implement new equipment to improve upon current processes.
•    Write and develop SOPS for current and new products, processes, and equipment.
•    Explore, design, evaluate and optimize processes to demonstrate the feasibility of potential new products and technologies.
•    Design, formalize, execute, analyze, and present experiments to meet strategic marketing objectives for the organization. 
•    Contribute to assay and process development, run novel cell isolations, assays and experiments, carefully document method and materials, and communicate findings.
•    Research, design and execute evaluation studies of new technologies for cell therapy starting material manufacturing.
•    Work on process development and improvements for Cell Solutions products. 
•    Manage inventory and supplies for R&D department: submit orders as necessary to ensure all required tasks can be completed, track outstanding orders, unpack/ date / number received supplies in an organized manner.
•    Take the lead on research and development necessary for custom client projects. 
•    Work with Scientific Director and Product Management Team to create an organized path for product creation and launch.
•    Train and ensure staff comply with all Standard Operating Procedures (SOPs) and quality systems, including current Good Manufacturing Practices (cGMPs) and current Good Tissue Practice (cGTPs), as required. 
•    Report, review and approve error/accident reports, deviations, related root cause analyses, corrective actions, preventive actions and follow-up, as applicable.  
•    Work with Isensix team to monitor system and respond to alerts.
•    Present and describe Cell Solutions products and processes to other departments, including sales and marketing.

Job Qualifications

•    BS/BA or MS in Life Science, or related field.
•    Must have 5+ years’ experience in related field, or equivalent combination of education, training, and experience.
•    Must have cell processing experience in industry, specific experience with cGMP or GLP preferred.
•    Experience with primary human cell culture and functional cell assays preferred.
•    Must have extensive experience with multicolor flow cytometry, specific experience with analysis using MACSQuant preferred.
•    Must understand biological and immunological principles and be able to apply these principles to laboratory experiments.
•    Must keep accurate and detailed laboratory records of all laboratory related activities.
•    Ability to advance projects through from inception to conclusion. 
•    Proficient use of Microsoft Office products including Word, Excel, Outlook, PowerPoint and Vizio.
 

IMPORTANT: A resume is required to be considered for this position. If you have not uploaded your resume in your candidate profile, please return to upload field and attach your resume/CV. 


Vaccine Mandate
Charles River is a U.S. Federal Contractor.  As a result, we must follow the Presidential Executive Order to mandate vaccinations, and ensure our employees are fully vaccinated against COVID-19.  Our main priority is the wellbeing, health, and safety of our people. We require proof of vaccination from all employees. 


Anyone with requests for disability-related and/or religious exemptions should contact Talent Acquisition (crrecruitment_US@crl.com) so that information can be provided about the accommodation process at Charles River.

 

About HemaCare 
HemaCare, a Charles River company, is a global leader and trusted brand in the customization of human-derived biological products and services for biomedical research, drug discovery, and cell and gene therapy development. HemaCare’s vertically integrated solutions support preclinical research, clinical studies from phases 1 to 3, and commercialization with high-quality RUO and GMP-compliant starting material and apheresis collections. 


 
In January 2020, HemaCare was acquired by Charles River Laboratories, an early-stage contract research organization (CRO). Combined with Charles River’s integrated, early-stage portfolio of discovery, safety assessment, and manufacturing support services, the acquisition creates a unique, comprehensive solution for researchers and cell therapy developers and manufacturers worldwide to help accelerate their critical programs from basic research and proof-of-concept to regulatory approval and commercialization. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs and enhances their productivity and effectiveness to increase speed to market. We work closely with our clients throughout the clinical process to maximize success and drive positive clinical outcomes. 


 
Together, with over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical and biotechnology companies, government agencies, and hospitals and academic institutions around the world. 


 
At HemaCare, we are passionate about our role in improving the quality of people’s lives. We have proudly supported the development of 100% of the current commercially available FDA-approved immunocellular therapies. Our mission is to provide a best-in-class portfolio of high quality, customizable human cellular material and services to support drug discovery, scientific research, and cell therapy. This resonates from our employees and impacts our customers because we know that every day is an opportunity to advance discoveries and make a difference in someone’s life. 


Equal Employment Opportunity
Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.


 
If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

 

For more information, please visit www.criver.com.


Nearest Major Market: Los Angeles

Job Segment: R&D, Research Scientist, Pharmaceutical, Cell Biology, Research, Science