In Vivo DART Toxicologist H/F

Req ID #:  221279

Evreux, FR, 27930

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.



Our Evreux facility


The Charles River site in Evreux, France is a unique 2-hectare site at the gateway to Normandy. It offers an innovative, dynamic and friendly scientific environment where almost 500 people work every day with the shared aim of contributing to the development of drug therapies, while respecting animal welfare.


Job summary


Working for our CRO, a world reference in the field, you will be our customers' key contact for the management of preclinical reproductive toxicology projects, and will ensure that they are properly conducted from start to finish.

In daily contact with our teams of technicians and scientists, you will be committed to providing them with your expertise to resolve any problems encountered.


Essential duties


As a Reproductive Toxicology Specialist, your responsibilities will include:

  • Act as Study Director for juvenile, developmental and reproductive toxicity studies conducted to the required scientific and regulatory standards in accordance with global regulatory guidelines [ICH/OECD].
  • Function as a single point of control for studies with overall responsibility for scientific, technical and regulatory conduct, scientific interpretation, documentation and communication of results,
  • Attend meetings with French and international customers, review commercial proposals for studies in this field.
  • Keep abreast of study designs and techniques, and suggest ideas for technical development where appropriate
  • Act as an expert in one or more of the following areas: fetal pathology, endocrinology, behavioral toxicity/neurotoxicity, juvenile toxicity
  • Maintain a scientific watch to provide expert advice to customers on customized study plans and study schedules based on drug development needs.
  • Represent the company at scientific meetings or on industry working parties, liaising with fellow Study Directors and other Charles River colleagues.


Job qualifications


Education : PhD in Toxicology, Veterinary Medicine or Pharmacy
Experience : Minimum of 10 years related experience in reproductive toxicology (research/lab animal/GLP environment). Experience in studies management required.
Others : You are recognized for your organization skills, pro-active and results-oriented attitude. You have excellent communication and reporting skills, both in English and French.


Our offer


  • A full time position
  • Salary: From €55,000 gross / year over 13 months
  • 100% health insurance, company restaurant, CSE 
  • Travel expenses, profit-sharing bonuses, home-office agreement, etc. 
  • Site not accessible by public transport - Means of transport essential


About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.  Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.


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