Electron Microscopy Technician 2

Req ID #:  50225

Durham, NC, US, 27703

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

 We are seeking an Electron Microscopy Technician 2 for our Safety Assessment site located in Durham, NC

This position will independently perform basic to intermediate Electron Microscopy sample preparation skills.  Participate in the documentation of all activities and may perform review of data.   May also assist with training of less experienced Electron Microscopy Technicians. May be trained as SD/PI per management’s discretion.


Essential Duties & Responsibilities:
  • Log in samples and set up study files for each protocol.
  • Trim tissue, process and embed both viral and tissue specimens.
  • Prepare solutions/reagents, cut thick/thin sections on the ultramicrotome, and stain slides/grids.
  • Examine samples on the transmission electron microscope (TEM), performing particle counts per SOPs, and take select pictures/images.
  • Examine tissue samples on the TEM working closely with the project pathologist, and take select pictures/images.
  • Perform darkroom procedures, i.e., develop negatives, process prints, and operate/maintain all ancillary equipment.
  • Label prints and write draft/final reports as required.
  • Communicate with clients on technical issues.
  • Understand and conduct all processes in compliance with Good Laboratory Practice (GLP) regulations, corporate Standard Operating Procedures (SOP), and the protocol.
  • Review and revise technical SOPs and forms.
  • Review documentation of functions performed as part of quality control requirements.
Minimum Qualifications:
  • Education:  Associate’s degree (A.A./A.S.) / Bachelor’s degree (B.A./B.S.) or equivalent in biology or related discipline.
  • Experience:  Minimum of 1 year related experience in electron microscopy.
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • Other: Placement at this levels requires successful completion /competency of the required tasks of the position preceding this level and continued ability to perform those tasks are required.  Must be able to perform effectively as a team member, accurately record data, follow verbal and written instructions, maintain a positive work atmosphere, communicate effectively, and interact in a professional manner with management, coworkers and sponsors.  Must be able to work independently.

About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.  Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2018.


Equal Employment Opportunity 


Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet


Nearest Major Market: Durham
Nearest Secondary Market: Raleigh

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