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Research Scientist II

Req ID #:  42103
Location: 

Ashland, OH, US

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

We are seeking a experienced Research Scientist II for our Safety Assessment group site located in Ashalnd, Oh.

BASIC SUMMARY:  

Serve as a Principal Investigator on toxico/pharmacokinetic studies in the Laboratory Sciences group. This includes interfacing with Study Directors and customers to design PK/TK methods/strategies for drug development programs. Experience in kinetics analysis non-clinical is required, also clinical preferred.  Must be proficient in Phoenix WinNonlin software required. Expertise in PK/PD modeling preferred.

ESSENTIAL DUTIES AND RESPONSIBILITIES:  

  • Serve as PK/TK kineticist determining and interpreting PK/TK endpoints for non-clinical and Clinical research studies
  • Conduct analysis using Phoenix WinNonlin sofware
  • Conduct work in compliance with regulatory requirements (GLP, EMA, etc., and local SOPs)
  • Interfaces with customers to understand the scientific and regulatory requirements for non-clinical and clinical bioanalysis studies
  • Coordinate PK/TK phase of the study in conjunction with appropriate departments and cross CRL sites
  • Generate high-quality PK/TK results and reports that comply with regulations and represent current best scientific principles
  • Work with Study Director/Program Managers and management to understand Sponsors needs
  • Mentor junior staff on PK/TK theory and applications of such
  • Provide input to management on business needs and development opporutnities
  • Attend scientific meetings, conferences and training courses to enhance job and professional skills.
  • Perform all other related duties as assigned.

QUALIFICATIONS:

  • Education: Ph.D. in Pharmacology, PharmD, or related field, with 2 years experience, MS with 2-5 years, or BS with 8-10 years of experience.  Candidates with more experience will be considered for higher level positions.
  • Experience:  2+ years PhD (etc, as above)
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.

Certification/Licensure:  N/A.

About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.  Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

 

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

 

With over 13,000 employees within 80 facilities in 23 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges.  Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

 

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 80% of the drugs approved by the FDA in 2017.

 

For more information, please visit www.criver.com.

 

Equal Employment Opportunity
Charles River Laboratories, Inc. is an Equal Opportunity Employer M/F/Disabled/Vet


Nearest Major Market: Cleveland
Nearest Secondary Market: Mansfield

Job Segment: Research Scientist, Scientific, Toxicology, Biotech, Science, Engineering, Research