Laboratory Team Lead (In vivo)

Req ID #:  71143

Wilmington, MA, US, 01887

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary


Charles River Labs seeks a hands-on Laboratory Team Lead (In vivo) to coordinate operations and technical execution of immunological methods in our humanized animal model production lab located in Wilmington, MA. 


The Laboratory Team Lead will be responsible for the following:


  • Provides technical oversight of protocol execution and hands on training for project team. 
  • Develop and update SOPs and train team members on execution of SOPs. 
  • Ensure welfare compliance and participate in the review and generation of IACUC protocols. 
  • Responsible for meeting production goals and technical execution of adoptive transfer methods. 
  • Performs, oversees and works closely with the project team on tissue culture and animal dosing experiments. Trains and participates directly in execution, providing technical oversight of hands on laboratory support. 
  • Works with aseptic techniques, BSL2 conditions, handling of mammalian cells. 
  • Oversees preclinical rodent animal manipulations and dosing and directly participates in the execution; including handling, injections and bleed procedures. 
  • Small animal surgery experience is favorable, but not required. 
  • Coordinate all aspects of project execution, including scheduling production studies, preparing study documents and ensuring project team preparedness. 
  • Works with client-facing teams to resolve/explain operational issues. 
  • Monitors metrics and performance data of procedures and production efficiency and provides reporting for forecasting purposes. 
  • Responsible for overseeing the daily operations of the laboratory management: 
  • Maintains supply chain of laboratory supplies, organizes laboratory materials/inventories, approves and coordinates receipts for orders, processes quotes/purchase orders from vendors. 
  • Maintains the calibration, safety and certification of lab equipment. 
  • Manages inventory of pre and post production animal subjects. 
  • Associate’s degree (A.S.) or equivalent in biological sciences or related discipline OR graduate of a collegiate veterinary technology program accredited by the American Veterinary Medical Association Committee on Veterinary Technician Education and Training Activities or equivalent program in veterinary technology. 
  • 5+ years related practical lab experience in a Pharmaceutical, Biotech or Contract Research Organization, or laboratory environment working directly with small animals (rodents) and mammalian cell culture.
  • An equivalent combination of education and lab management experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • Experience creating/editing/training others with Standard Operating Procedures.
  • Experience leading teams.
  • Project management skills including experience in forecasting and meeting deadlines.
  • Strong attention to detail and accuracy.
  • Strong organization and prioritization skills. 
  • Effective verbal and written communication skills.
  • Proficient in MS Office Suite.



  • Bachelor’s degree (B.S.) or equivalent in biological sciences or related discipline.


Physical Demands:

  • While performing the duties of the job, the employee is regularly required to sit, use hands to finger, handle, or feel objects, tools or controls; talk, hear and type/work at a computer.
  • Specific vision abilities required by this job include close vision and the ability to adjust focus.


Work Environment:

  • General laboratory working conditions, the noise level in the work environment is usually moderate.  Exposure to animal odors and dander is inherent to this position.


About Research Models & Services
Fundamental to basic research and discovery is the use of in vivo models to help identify disease targets and determine potential biological pathways that regulate the condition.  As the world’s leader in the production and distribution of the highest quality research animal, with 1 out of 2 animal models produced for preclinical research globally, we understand the importance of this step. With seven decades of experience, our expertise is unmatched, allowing us to provide you with the perfect model, including disease-specific and preconditioned options, for basic research and beyond.

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.


Equal Employment Opportunity

Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet.


If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.


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