Embryology Technologist

Req ID #:  89221
Location: 

Wilmington, MA, US, 01887

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

 

The GEMS Embryology department is looking for an Embryology Technologist who will maintain and monitor the production of embryos via in vitro fertilization (IVF), conduct embryo transfer procedures, collect embryos from naturally mated animals, conduct embryo and sperm cryopreservation, conduct quality control (QC) procedures on cryopreserved material, maintain cryo-inventory and help keep track of Key Performance Indicators (KPI) of embryology program.  In addition, the Embryology Technologist will be responsible for knowing how to work within gnotobiotic isolators, individual ventilated cages (IVC) for maintenance of pseudo-pregnant colonies for embryo transfer.

 

 

ESSENTIAL DUTIES AND RESPONSIBILITIES:

 

  • Generates rodent embryos using IVF technology.
  • Collection of embryos from oviduct and uterine tissue from naturally mated rodents.
  • Collection of spermatozoa from rodents for routine sperm cryopreservation. 
  • Collection of embryos from IVF and natural mating for routine embryo cryopreservation.
  • Conduct QC procedure for cryopreserved material.
  • Conduct embryo transfer (oviductal/uterine) using aspect surgical techniques.
  • Maintain cryo-inventory and ensure maintenance of cryo storage units.
  • Conduct both Mouse Embryo Assay and Sperm Motility Assay.
  • Experience performing animal husbandry using gnotobiotic isolators, including monitoring animal’s food, water and bedding conditions.  
  • Introduction into gnotobiotic isolators basic husbandry supplies including food, cages, bedding, water and environmental enrichment.
  • Preference for individuals with germ-free isolator husbandry experience.
  • Comfortable handling rodents (mice and rats), including restraining of animals for collection of fecal pellets, ear/tail sampling as well as tagging animals for identification.
  • Must be comfortable performing mouse/rat health checks and interacting with veterinary staff as necessary.
  • Assist supervisors with mentoring and training of new personnel. 
  • May act as team leader in specific departmental projects.
  • Understand and comply with all Standard Operating Procedures (SOPs).
  • Strictly follow all biosecurity procedures necessary to maintain isolator integrity and animal health status, including the proper sterilization and entry of supplies/animals into gnotobiotic isolators. 
  • Ensure proper record-keeping and report preparation; ensure data entry into Internet Colony Management (ICM).
  • Ensure compliance with all local, state and federal laws governing the use of research animals.
  • Demonstrated performance to use knowledge and skills when needed.
  • Ability to maintain detailed records and observations.
  • Ability to work under deadlines with general guidance.
  • Excellent organization skill and demonstrated ability to accurately complete detailed work.
  • Weekends and holidays may be require.
  • Perform general housekeeping and adhere to safety procedures.
  • General computer skills and ability to quickly learn and master computer programs, databases and other applications. 
  • Perform all other related duties as assigned.

 

MINIMUM QUALIFICATIONS:

  • High school diploma with preference with Associate degree (A.A. /A.S.) or higher degree equivalent in Biological Science, Lab Animal Science or related discipline. 
  • 1 years related experience and/or training.
    • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • Proficient in computers:   (ie:  MS OfficeSuite and computer knowledge of databases).
  • Must possess a high level of initiative and ability to work with little supervision.
  • Broad knowledge of biology laboratory practices.
  • Knowledge and experience in rodent disease models.


PREFERRED QUALIFICATIONS:

  • AALAS certification at the ALATG.

About Research Models & Services
Fundamental to basic research and discovery is the use of in vivo models to help identify disease targets and determine potential biological pathways that regulate the condition.  As the world’s leader in the production and distribution of the highest quality research animal, with 1 out of 2 animal models produced for preclinical research globally, we understand the importance of this step. With seven decades of experience, our expertise is unmatched, allowing us to provide you with the perfect model, including disease-specific and preconditioned options, for basic research and beyond.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

 

With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.

 

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.

 

Equal Employment Opportunity

Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet.

 

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

 

For more information, please visit www.criver.com.


Nearest Major Market: Boston

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