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Senior Assistant Scientist

Req ID:  46364

Tranent, ELN, GB, EH33 2NE

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

The Department of Regulatory ADME and Discovery Sciences provides support to the pharmaceutical, veterinary pharmaceutical and chemical/agrochemical industries by evaluating the metabolism and disposition (ADME) of new chemical and biological entities in vitro and in vivo in a variety of test species. 


We are looking to recruit Senior Assistant Scientist to join the in vitro metabolism team.  The role of this team is to understand the ADME properties of novel pharmaceutical and chemical agents in a variety of in vitro test systems from multiple species including human.  Working in close contact with our clients, the study directors, the management team and the internal Charles River services you will be expected to contribute to the conduct of projects to support the smooth and swift progression of drug candidates through preclinical evaluation and beyond. 



Your responsibilities as a Senior Assistant Scientist will include the following:


  • High quality conduct of assigned in vitro metabolism studies to support compound registration
  • Accurate and detailed documentation of activities
  • Preparation of data and reports for issue to clients
  • Engagement in staff training and development programs
  • Supervision of junior staff (where required)


Applicants should be educated to degree level in chemistry or a life science related discipline with a significant biology component.  You should also have a minimum 18 months relevant laboratory experience, with particular emphasis on the conduct of in vitro studies.



Specific criteria that you are required to meet include:

  1. Relevant qualifications, specifically a minimum of a scientific degree in a relevant discipline.
  2. Excellent communication and organisation skills as well as an ability to work flexibly and to tight deadlines
  3. A minimum of 18 months relevant laboratory experience (consideration will be given to candidates with less experience, but appointment would be at a lower level).
  4. A working knowledge of Microsoft Office and graphing/statistics (such as Graphpad Prism) software.


Salary for this position will be agreed depending on the candidates relevant skills and experience.


All internal applicants should apply through the careers page on Talent Hub.


The closing date for this position is Thursday, 19 September 2019.

About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.  Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2018.