Group Leader - Chemistry

Req ID:  93579

Saffron Walden, GB, CB10 1XL

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

We are pleased to announce an exciting new opportunity for a talented, highly motivated individual to provide scientific and managerial leadership within the Chemistry department at our drug discovery facilities in Chesterford Park, Saffron Walden, UK. In addition to management, mentoring and development of scientists within their team, the successful candidate will work with a diverse range of global organisations, providing discipline scientific leadership as well as influencing internal project teams to drive scientific excellence.   


 Main Responsibilities 
•    To provide managerial leadership within the Chemistry department, with responsibility for health and safety, performance management, objective setting, providing feedback and motivating and developing staff. 
•    To represent the Early Discovery management team to all staff and to contribute to the management and performance of the Chemistry department.
•    To provide chemistry and drug discovery services to clients using expertise and initiative to define and deliver agreed project objectives.
•    To provide scientific leadership to project teams by designing, influencing and co-coordinating medicinal chemistry work plans, and using sound scientific decision making and creative problem solving skills to achieve project goals.
•    To contribute to Business Development activities.
•    To contribute as needed to operational leadership within the department, coordinating internal processes such a laboratory management and health and safety. 
•    To proactively influence scientific and IT infrastructure, working to simplify and enhance processes to improve effectiveness.


•    A first degree in chemistry or a closely related subject.
•    Excellent interpersonal, communication and presentation skills, as demonstrated both internally and externally with clients.
•    Experience in motivating and developing others, e.g. management or supervision/mentoring of junior scientists.
•    A positive role model with a ‘can-do’ attitude, who contributes to departmental goals and promotes best practice.
•    Broad experience in medicinal chemistry across different phases of drug discovery (e.g. active-to-hit, hit-to-lead, lead optimisation). 
•    Strong track record of scientific impact in projects, as evidenced by publications and/or co-inventorship on multiple patent applications.
•    Experience of designing and coordinating chemistry work plans for others, either at CRL or with third parties.
•    Exceptional problem solving skills, sound scientific judgement and high quality decision making, which has impacted positively on project deliverables.
•    Pro-active member of the Chemistry management team.
•    Awareness of how project resources and finances are managed within an acceptable budget.
•    A dynamic and flexible approach towards achieving client-based objectives, with developing strategic thinking.
•    Ability to prepare high quality scientific documents to challenging deadlines.
•    High quality contributions to Business Development proposals and face to face meetings.
•    Models the Charles River Values of Care, Lead, Own and Collaborate.
•    Must be able to work at Chesterford Park, Saffron Walden, UK.


All applicants must have the right to work in the UK before being considered. 


Closing Date: Friday 11th June 2021 

About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.