Senior Scientist

Req ID:  81791

Portishead, GB, BS20 7AW

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

We are seeking a Senior Scientist with focus on project management and coordination for our in Pharmacology team currently located in Portishead, UK.

In this position, you will lead/coordinate in vivo Pharmacology projects by functioning as study monitor, collecting and analyzing data, supporting scheduling of studies, by resourcing of personnel and of project meetings. You will organize workflow, mentor younger members of the team, supervise technical details and deliverables necessary to meet project timelines and budgets by also liaising with other teams on site. 
You will be expected to deliver exceptional product quality and customer service through frequent, open communications particularly with internal stakeholders. You will also take a leading role on the marketing of Pharmacology material. 
This position is particularly directed to a senior technical professional or an in vivo scientist with experience of pharmaco-immunology models in rodents, passion for science and basic research.


Key Responsibilities:
•    Support project management of research projects within the in vivo pharmacology team liaising with the other teams.
•    Prepare reports and present results to different audiences
•    Monitor projects from protocol design to study archiving including performing technical work


We are seeking a candidate who:
•    Has the ability to perform under pressure in a fast-paced, multitask, deadline-orientated environment.
•    Has excellent computer skills, specifically with all the Microsoft Office packet. 
•    Has experience with GraphPad (for data presentation and statistical analysis)
•    Has experience with reference manager software and PubMed usage
•    Is detail-orientated with optimal written and oral communications skills
•    Has knowledge of study protocols and in vivo work. Experience in immunology in vivo models (e.g EAE, EAU, SLE, Colitis, Psoriasis), is desirable.
•    Has the ability to work independently and as a member of an integrated team.
•    Holds a Home Office Personal License under the Animals (Scientific Procedures) Act 1986.
•    Has experience performing compound formulations, regulated procedures, administering substances by a variety of routes and performing blood sampling and dissection of small rodents
•    Has experience working under the Code of Practice for the housing and care of animals used in scientific procedures.
•    Works within defined Standard Operational Procedures (SOPs) with a keen eye for detail.
•    Has passion for working with animals and their welfare.

About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.