Associate Research Director

Req ID #:  97061

Morrisville, NC, US, 27560

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

We are seeking an Associate Research Director for our Discovery site located in Morrisville, NC.

The following are responsibilities related to the Associate Research Director:

Lead and manage scientists focused on conducting in vitro and in vivo pharmacology to advance leads from preclinical discovery thru to early clinical development.  Design, execute, and ensure quality of in vivo efficacy pharmacology studies. Apply expertise in cancer biologics drug discovery to influence overall Oncology Research strategy and project progression with a focus on immunotherapies and syngeneic models.

•    Guide the planning and execution of scientific research and/or critical development strategies.  
•    Provide scientific oversight of study design, preparation of protocols, interpretation and reporting of data.
•    Serve as project manager and study director – develop, design, validate, interpret, prepare reports and conduct studies as assigned.
•    Develop and maintain client/sponsor relationships and participate in business development.
•    Serve as initial contact for new contracts and provide project outlines and pricing in collaboration with client services/account management.
•    May recommend new capabilities, technologies, and techniques.
•    Contribute to problem resolution of scientific and technical study issues. 
•    Responsible for regulatory compliance and quality analysis of study data.
•    Perform testing facility management duties for the site as delegated by senior management.
•    Ensure all appropriate parties (e.g. client services, account management, field sales, company management) are aware of/involved in client/sponsor negotiations. 
•    Direct activities of assigned group(s) to ensure effective performance of function.
•    Ensure that management training and development needs are identified and programs initiated.  Direct the development of departmental orientation and other training programs.  
•    Monitor performance of direct reports.  Provide regular coaching and counseling.  Prepare and deliver salary and performance reviews; review and approve performance and salary appraisals initiated by direct reports.
•    Monitor and determine appropriate levels of departmental overtime.  Review and approve vacation/time off requests for direct reports.  
•    Develop short- and long-range operating objectives, organizational structure, and staffing requirements.  Oversee the development of a departmental plan for backup and succession of key departmental personnel.
•    Develop and recommend departmental budget.  Authorize expenditures in accordance with budget.  Approve budget and expenses of subordinates.
•    Ensure optimum performance of group function.  Recommend and implement techniques to improve productivity, increase efficiencies, cut costs, take advantage of opportunities, and maintain state-of-the-art practices.

Job Qualifications

The following are minimum qualifications related to the Associate Research Director position:

  • Education:   Doctoral degree (PhD, DVM, MD) or equivalent in related discipline.
  • Experience:  Seven to ten years experience in the contract research or pharmaceutical industry conducting scientific research in oncology. Postdoctoral experience preferred with demonstrated research capability as demonstrated by publications in peer-reviewed journals in related fields such as oncology and immunology. Extensive experience with in vivo cancer models, including tumor xenograft models, primary tumor models, and syngeneic and genetically-engineered mouse models. Expertise in multiple fields of cancer biology, including cancer immunology, cancer stem cells, tumor cell survival, and drug resistance. A strong knowledge of oncology indications (solid tumors and hematological malignancies), and standard of care treatments.  Experience with financial business planning, project management and technical support sales experience preferred. Management or demonstrated leadership experience preferred. 
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.


About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 320 patents and 74 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.


Equal Employment Opportunity

Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet.


If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.


For more information, please visit

Nearest Major Market: Raleigh

Job Segment: Research Associate, Genetics, Manager, Biotech, Research, Science, Management