Share this Job

Technician I Mammalian Cell Banking

Req ID #:  43803
Location: 

Malvern, PA, US, 19355

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

We are seeking a Technician I Mammalian Cell Banking for our Biologics Testing Solutions site located in Malvern, PA.

 

The following are minimum requirements related to the Technician I Mammalian Cell Banking position.

Basic Summary

Under direct supervision, responsible for performing basic daily laboratory and clean room tasks as they relate to the operations performed within the Manufacturing department, including cell banking and vaccine preparation activities. 

ESSENTIAL DUTIES AND RESPONSIBILITIES:

  • Expand and harvest a mammalian or insect cell line or propagate and harvest a virus or vaccine candidate to generate several hundred vials of a Cell Bank or Virus Bank within class 100/10,000 clean room environments while gowned appropriately.
  • Work within a class 100 biological safety cabinet and maintain a sterile aseptic environment.
  • Ability to appropriately culture and manipulate varying cell lines.
  • Work within a clean room suite while gowned in clean room attire.
  • Practice good aseptic technique and sterile procedures.
  • Prepare stock solutions and growth media to be used in any Manufacturing campaigns.
  • Perform calibration, monitoring and cleaning of laboratory equipment associated with the manufacturing of cell banks.
  • Maintain a clean laboratory and working environment and monitor laboratory equipment specifications.
  • Adhere to company policies and standard operating procedures (SOPs) as related to cGMP compliance and good documentation practices.
  • Perform all other related duties as assigned.
  • Maintain a safe working environment by adhering to company policies and procedures.

QUALIFICATIONS:

  • Education: Bachelor’s degree (B.A./B.S.) in a scientific field or related discipline.  
  • Experience: 0-2 years related experience in a biological laboratory or GMP facility.  An equivalent combination of education and experience may be accepted as a satisfactory substitute for specific education and experience listed above.
  • Certification/Licensure: N/A
  • Other: Ability to write SOPs and other documentation; proficiency in MS Word, ability to perform tasks independently.

BASIC SUMMARY:

Under direct supervision, responsible for performing basic daily laboratory and clean room tasks as they relate to the operations performed within the Manufacturing department, including cell banking and vaccine preparation activities. 

ESSENTIAL DUTIES AND RESPONSIBILITIES:

  • Expand and harvest a mammalian or insect cell line or propagate and harvest a virus or vaccine candidate to generate several hundred vials of a Cell Bank or Virus Bank within class 100/10,000 clean room environments while gowned appropriately.
  • Work within a class 100 biological safety cabinet and maintain a sterile aseptic environment.
  • Ability to appropriately culture and manipulate varying cell lines.
  • Work within a clean room suite while gowned in clean room attire.
  • Practice good aseptic technique and sterile procedures.
  • Prepare stock solutions and growth media to be used in any Manufacturing campaigns.
  • Perform calibration, monitoring and cleaning of laboratory equipment associated with the manufacturing of cell banks.
  • Maintain a clean laboratory and working environment and monitor laboratory equipment specifications.
  • Adhere to company policies and standard operating procedures (SOPs) as related to cGMP compliance and good documentation practices.
  • Perform all other related duties as assigned.
  • Maintain a safe working environment by adhering to company policies and procedures.

QUALIFICATIONS:

  • Education: Bachelor’s degree (B.A./B.S.) in a scientific field or related discipline.  
  • Experience: 0-2 years related experience in a biological laboratory or GMP facility.  An equivalent combination of education and experience may be accepted as a satisfactory substitute for specific education and experience listed above.
  • Certification/Licensure: N/A
  • Other: Ability to write SOPs and other documentation; proficiency in MS Word, ability to perform tasks independently.

About Biologics Testing Solutions

With more than 50 years of experience and proven regulatory expertise, the Charles River Biologics group can address challenging projects for biotechnology and pharmaceutical companies worldwide. Offering a variety of services such as contamination and impurity testing, protein characterization, bioassays, viral clearance studies and stability and lot release programs, we support clients throughout the biologic development cycle, from the establishment and characterization of cell banks through preclinical and clinical studies to marketed products. Whether clients need stand-alone services, a unique package of testing, or insourced support, our Biologics group can create a custom solution to suit their needs.  Each year more than 20,000 biologic testing reports are sent each and over 200 licenses products are supported by our biologics testing solutions team.

 

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

 

With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017.

 

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2018.

 

Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet. If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

 

 


Nearest Major Market: Philadelphia

Job Segment: Biotech, Technician, Pharmaceutical, Laboratory, Science, Technology, Research