Viral Vectors - Subject Matter Expert

Req ID:  153811
Location: 

Keele, GB, ST5 5SP


At Charles River, we are passionate about improving the quality of people’s lives. When you join our global family, you will help create healthier lives for millions of patients and their families. 

 

Charles River employees are innovative thinkers, who are dedicated to continuous learning and improvement. We will empower you with the resources you need to grow and develop in your career. 

 

As a Charles River employee, you will be part of an industry-leading, customer-focused company at the forefront of drug development. Your skills will play a key role in bringing life-saving therapies to market faster through simpler, quicker, and more digitalized processes. Whether you are in lab operations, finance, IT, sales, or another area, when you work at Charles River, you will be the difference every day for patients across the globe.

 

IMPORTANT:   In order to be considered for this position, a resume/CV must be uploaded and submitted during the application process.  Please make sure work history and education are added correctly.   

Job Summary

Cobra Biologics, is part of the wider end-to-end service provision for Cell & Gene Therapies within Charles River Laboratories. As such, to support Cobra’s growth programme, and the C&GT portfolio, we are looking for a Subject Matter Expert (SME) who has experience in the development and/or manufacturing of gene therapy viral vectors. They will have recent direct experience of viral vector development, scale up and production using mammalian cultures systems at various scales.  

Profile and Requirements

The Technical Lead – Viral Vectors, will provide both strategic and tactical scientific and technical leadership, along with Manufacturing Science and Technology oversight across the breadth of the viral vector development and manufacturing service offerings. Their main duties of the role are:

•    Identify, refine and plan technical programme requirements and develop work schedules.  Perform rolling review and update of work schedules and lead troubleshooting as required.

•    Liaise with team members, management, suppliers and clients to ensure projects are completed to agreed standards, on time and within budget.

•    Identify, monitor and manage risks and develop contingency plans.

•    Drive and deliver MSAT initiatives through analysis of existing operations, identification of areas for improvement and standardisation of service offerings including monitoring and reporting of technical quality standards. 

•    Keep up-to-date with industry trends and developments.  Represent and promote the company through conference attendance and sales meetings as required.

•    Provide technical collaboration to support mergers and acquisitions functions.

•    Motivate and mentor scientific and technical staff and support progression plans to enable continued improvement in technical capability and staff development.

•    Communicate effectively with teams and programme stakeholders on challenges, failures, and successes.


Ideally you will:


•    Be educated to degree level or equivalent in a Life Science or related discipline in the contract development and / A significant track record in contract development and/or contract manufacturing for the Life Sciences sector
•    Understand the biologics manufacturing services market
•    Thorough understanding of the process required to develop a viral vector biologic product
•    Extensive customer interaction experience
•    Strong strategic thinking ability
•    Direct experience in the development, delivery and technology-transfer of manufacturing processes for ATMPs
•    Knowledge and experience of GMP quality systems
 

 

 

IMPORTANT: A resume is required to be considered for this position. If you have not uploaded your resume in your candidate profile, please return to upload field and attach your resume/CV. 
 

About Corporate Functions
The Corporate Functions provide operational support across Charles River in areas such as Human Resources, Finance, IT, Legal, Sales, Quality Assurance, Marketing, and Corporate Development. They partner with their colleagues across the company to develop and drive strategies and to set global standards. The functions are essential to providing a bridge between strategic vision and operational readiness, to ensure ongoing functional innovation and capability improvement.  
 

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
 

With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.
 

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.
 

For more information, please visit www.criver.com.