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Associate Research Scientist/Fetal Pathology

Req ID #:  41327
Location: 

Horsham, PA, US, 19044

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

 

BASIC SUMMARY:  

Responsible for independently performing fetal pathology assessments, recording results, and where necessary, preparing phase reports delineating fetal pathology findings.  With minimal supervision, function as an Individual Scientist/Principal investigator on assigned studies of basic complexity and participate in method development and validation activities.

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ESSENTIAL DUTIES AND RESPONSIBILITIES:  

• Prepare and evaluate fetal soft tissue and skeletal specimens as required according to Standard Operating Procedures (SOPs), including writing edits, taking photographs, answering internal and external audits and drafting computer protocol requests.

• Function as a primary contact, with guidance from senior scientific staff, for the planning and execution of Sponsor visits related to fetal pathology.  May serve as a consultant in fetal pathology-related issues.

• Assist in the oversight of the fetal pathology laboratory, including method development and process refinement, study-related problem resolution, technique evaluation, SOP revisions, department inspections, and equipment maintenance.  Recommend and implement techniques to improve productivity, increase efficiencies, cut costs, take advantage of opportunities, and maintain state-of-the-art practices.

• Provide leadership and technical guidance to less experienced staff; provide technical guidance to the research staff.

• Provide updates of the fetal evaluation schedule to ensure internal/reporting milestones are met.  

• Oversee study start-up procedures requiring cross-departmental interaction with all key study personnel.

• Assist in generating study protocols and laboratory-based procedures for various regulatory guidelines.

• Ensure that all fetal soft tissue and skeletal data for the studies are accurately recorded and verified.

• Assist with fetal pathology confirmation, where appropriate. 

• Generate high-quality phase reports appropriate for assigned studies, including review of basic to complex data and writing comprehensive narratives detailing all test article effects.

• Ensure project is in compliance with GLP regulations as they apply to the conduct of nonclinical research.

• Ensure adequate supplies of all equipment/materials needed for fetal evaluation.

• Pack and archive fetal soft tissue and skeletal specimens according to SOPs.

• Train laboratory personnel in preparation and evaluation of fetal soft tissue and skeletal specimens, including data entry.

• Prepare reagents (KOH, etc) for fetal processing.

• May provide scientific expertise for experimental design and other aspects of research studies as needed.

• Assist in the interview and selection of qualified fetal pathology personnel.  

• Identify training and development needs of fetal pathology staff.  Assist in the development, implementation and delivery of departmental training programs.  

• May assist in development of departmental budget.

• Attend scientific meetings, conferences and training courses to enhance job and professional skills.

• Perform all other related duties as assigned.

 

QUALIFICATIONS:

• Education:  Bachelor’s degree in a scientific discipline or equivalent, including coursework in anatomy and biology.  Related Master’s degree (M.S./M.A).

• Experience: 8 to 12 years related experience in fetal morphological assessments including 10 years related experience in contract research or pharmaceutical industry.  

• An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.

• Certification/Licensure:  Fetal Pathology certification required.  

• Other:  Demonstrated success in technical proficiency, scientific creativity, collaboration with others and independent thought.  Works on problems of diverse scope in which analysis of data requires evaluation of identifiable factors.  Exercises judgment within generally defined practices and policies in selecting methods and techniques for obtaining solutions. Effective written and verbal communication skills. Ability to handle multiple projects, prioritize work and meet deadlines. Proficiency in the use of standard software including Microsoft® Excel, Word, PowerPoint, etc. and with standard laboratory calculations.

 

PHYSICAL DEMANDS:

• Regularly provides information to and receives information from/through various technologies, media, sources and contacts.  Must be able to accurately exchange accurate information in these situations.

• Regularly operate a computer and other office productivity machinery, such as a calculator, copy machine, and computer printer.  

• Specific vision abilities required by this job include regular use of close vision and the ability to adjust focus. 

• Must be able to regularly wear a safety equipment and clothing in compliance with OSHA regulations and company SOPs.

• Regularly record data by hand or on a computer terminal.

• Regularly stand approximately four to six hours a day.

• May sit up to 8 hours a day.

• Must be able to regularly observe physical attributes of species.  

• Must be able to occasionally lift and manipulate up to 50 pounds.

• Must be able to occasionally manipulate and remove objects from shelves one and one half to six and one half feet above the floor (with the aid of a step stool).

• Must be able to occasionally work in spaces as narrow as 2 feet.

• Must be able to regularly communicate with other personnel regarding all aspects of a study.

• Must be able to occasionally push wheeled carts weighing up to 1200 pounds.

 

WORK ENVIRONMENT:

• General office working conditions.

• The noise level in the work environment is usually quiet. 

• May occasionally be exposed to fumes or airborne particles, unpleasant odors, and/or wet, humid and/or extreme temperature conditions. 

• While performing the duties of this job the employee may occasionally be required to wear protective clothing (goggles, face shield, surgical mask, cap, gloves, scrubs, boots), work near toxic or caustic chemicals, work with biohazards, and/or work with live animals with risk of exposure to allergens and/or zoonotic diseases.  

 

COMMENTS:

• This position requires occasional domestic travel.  

• This position may require occasional weekend and holiday work.  

Job Summary

Designs and executes a total rewards vision and strategy to support the company’s short-and long-term business objectives. Develops, implements, and administers company-wide job classification systems, salary structures, recognition plans, company stock plan programs, incentive plans, sales compensation, executive compensation, and/or short/long term incentive programs that will attract and retain talent. Shapes, communicates and administers employee benefits including health and welfare, retirement/401 K planning, wellness plans/initiatives, and/or health fairs. Maintains relationships with plan brokers, third party administrators, and investment advisors. Regularly monitors the competitiveness of current total rewards programs and ensures pay/benefits are aligned with the market by analyzing survey/benchmark data. Manages all annual total rewards processes including compensation review cycle, equity grant process, incentive compensation payout and planning, benefits renewal process, and open enrollment. Partners with HRIS on the creation, testing and maintenance of compensation and benefits system requirements and data integrity. Provides counseling and communications of compensation and benefits to employees and management.

We are seeking a [Insert Job Title] for our [Insert Business Group] site located [Insert Location].

About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.  Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

 

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

 

With over 13,000 employees within 80 facilities in 23 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges.  Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

 

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 80% of the drugs approved by the FDA in 2017.

 

For more information, please visit www.criver.com.

 

Equal Employment Opportunity
Charles River Laboratories, Inc. is an Equal Opportunity Employer M/F/Disabled/Vet


Nearest Major Market: Philadelphia

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