Scientist/Senior Scientist

Req ID:  66673

Harlow, GB, CM19 5TR Saffron Walden, GB, CB10 1XL

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

Our teams in Saffron Walden and Harlow are looking to recruit for Scientists/Senior Scientists on initial 12 month contracts with potential to go permanent following this period. 
These opportunities will place you as part of a cross-functional team working at the forefront of drug discovery, interacting with other groups within the organisation including computational chemistry, chemistry, compound management and in vitro and in vivo DMPK. These are fantastic opportunities that would allow you to work in a challenging and dynamic environment that provides the ideal opportunity to showcase your expertise in contributing to the discovery of potential new medicines. You will also be given the chance to develop your own skills via interaction with scientists from diverse cultural and scientific backgrounds.  
You will be self-motivated and enthusiastic about working in the lab and will have experience with plate-based screening and assay development, ideally gained within industry or an academic screening environment. 
The main responsibility in the roles will be to work on a range of biochemical and cellular assay formats, solving challenging problems, analysing and reporting data to advance client drug discovery projects. You'll be working in a cross-functional working environment and will be collaborating with teams in Chemistry and DMPK in order to drive projects forward. 
 Our ideal candidate will have a degree or PhD level qualification, between 1 and 3 years' relevant experience, and a passion for applying scientific expertise to drug discovery collaborations. Adept at problem solving and in working as part of a multi-disciplinary team, you will need to possess the flexibility required to work in a goal-oriented environment, as well as:
* Experience in developing, optimising and executing in vitro biological assays (biochemical, cell based) for HTS and small molecule drug discovery projects.
* The ability to QC equipment and data and use this experience to troubleshoot assays
* Experience at high throughput screening or plate-based SAR generation assays
* A pro-active and positive problem solving mindset
* The ability to suggest new ideas or initiatives that impact upon project progress
* An awareness of the relevant scientific literature and contemporary laboratory practices
* An ability to work to tight deadlines
* Strong organizational skills
* A desire to work in cross-functional teams where your data will have a direct impact on project goals
* A willingness to interact with other members of the department, sharing assay development and screening best practises
* Presenting your own work confidently to both internal project teams and in client meetings
* An ability to work in a safe manner at all times ensuring procedures/SOPs are adhered to



NB In order to fulfil our requirements under our COVID-19 working policy, the successful candidates may be asked to work outside of the standard working pattern of Monday to Friday, 9 am to 5.30 pm.  Please can you indicate any preferences for times/days to be worked on your application. 


About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.