Share this Job

Research Leader - Pharmaceutical Sciences

Req ID:  44231

Harlow, ESS, GB, CM19 5TR

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

We are pleased to announce an exciting new opportunity for a talented, highly motivated Research Leader Pharmaceutical Sciences to join our team at our drug discovery facilities in Harlow, UK. 


This role will see you working with a diverse range of global organisations, providing key scientific contributions to support integrated small molecule drug discovery programs. Main responsibilities of the role include: 
·       Act as subject matter specialist, advising integrated project teams on formulation aspects 
·       A discipline lead who positively drives aspects of scientific innovation and strategy 
·       Liaise with colleagues in Medicinal Chemistry, DMPK and Pharmacology departments to provide formulation options for compounds that are challenging to dose in-vivo 
·       Design and undertake formulation screening studies for novel APIs 
·       Transfer of technical knowledge to third party GMP CROs/CMOs 
·       To provide scientific expertise to project teams by designing, influencing and co-coordinating work plans, and using sound scientific decision making and creative problem solving skills to achieve project goals. 
·       To contribute to Business Development activities


Job Requirements

Key requirements of the Research Leader Pharmaceutical Sciences are: 
·       A first degree in Pharmaceutical Sciences (or equivalent) or a closely related subject 
·       Extensive industrial experience, working in drug discovery or development 
·       Experience of developing discovery phase formulations for i.v. nd p.o. administration; experience with topical formulations would be an advantage 
·       High degree of competency with LC-MS instrumentation 
·       Excellent interpersonal, communication and presentation skills, as demonstrated both internally and externally with clients 
·       Experience in motivating and developing others, e.g. mentoring of junior scientists 
·       A positive role model with a ‘can-do’ attitude, who contributes to departmental goals and promotes best practice 
·       Strong track record of scientific impact in projects 
·       High degree of commercial awareness, ideally gained in a CRO environment 
·       Experience of designing and coordinating work plans for others
·       Exceptional problem solving skills, sound scientific judgement and high quality decision making, which has impacted positively on project deliverables 
·       Awareness of how project resources and finances are managed within an acceptable budget. 
·       A dynamic and flexible approach towards achieving client-based objectives, with developing strategic thinking 
·       Ability to prepare high quality scientific documents to challenging deadlines 
·       High quality contributions to Business Development proposals and face to face meetings 
·       Models the Charles River Values of Care, Lead, Own and Collaborate 
·       This position is based in Harlow, Essex, UK



About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017.


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2018.