Immunopathology Technician 3

Req ID #:  47728

Durham, NC, US, 27703

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

  • Perform basic to complex tasks associated with or in support of immunopathology laboratory procedures and collect and record/document research data in compliance with Good Laboratory Practices (GLPs), Standard Operating Procedures (SOPs), study protocols and company policies/practices.
  • Handle unfixed human and animal tissues (e.g. preparation of frozen OCT-embedded tissue blocks and cryotomy).
  • Perform dilution calculations, moderately complex chemistry, and problem solving.
  • Perform troubleshooting and methods design with study pathologists.
  • Ensure the use of appropriate positive/negative tissue controls; fixations, staining procedures/techniques, and solution preparation.
  • Input, print and edit computer entries (e.g., laboratory data).
  • Receive samples and complete tracking documentation.
  • Review documentation of functions performed as part of quality control requirements.
  • Perform more difficult/strenuous immunopathology tasks (e.g. high volume staining, simultaneous staining of different procedures, high volume cryotomy, precomplexes, and/or cross-reactivity staining, etc.)
  • Optimize commercial & sponsor provided antibodies

REQUIRES:  BS Degree or equiv exp in lab science field PLUS 4 or more years exp in biology, chemistry/pharmacy. GLP exp reqd.   


About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.  Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2018.


Equal Employment Opportunity 


Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet


Nearest Major Market: Durham
Nearest Secondary Market: Raleigh

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