Electron Microscopy Tech 3 - SIGN ON BONUS $750

Req ID #:  94937

Durham, NC, US, 27703

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary

Independently perform basic to advanced Electron Microscopy sample preparation skills.  Participate in the documentation of all activities and review of data.   Train less experienced Electron Microscopy Technicians.  Monitor and report process improvements, including review and revision of technical SOPs and forms.  May serve as Study Director or Principal Investigator, as assigned. 
•    Independently trim tissue and process and embed both viral and tissue specimens.
•    Prepare solutions/reagents, cut thick/thin sections on the ultramicrotome, and stain slides/grids.
•    Examine samples on the transmission electron microscope (TEM), performing particle counts per SOPs, and take select pictures/images.
•    Examine tissue samples on the TEM working closely with the project pathologist, and take select pictures/images.
•    Change filaments in the transmission electron microscopes as needed.
•    Process specimens for Scanning Electron Microscopy (SEM) and oversee microscopist at off-site scope.
•    Perform darkroom procedures, i.e., develop negatives, process prints, and operate/maintain all ancillary darkroom equipment. 
•    Label prints and write draft/final reports as required. 
•    Communicate with clients on technical issues.
•    Understand and conduct all processes in compliance with Good Laboratory Practice (GLP) regulations, corporate Standard Operating Procedures (SOP), and the protocol.
•    May serve as Study Director or Principal Investigator serving as the single point of control for a specific in-house study and as such is responsible for the overall technical conduct of the study.
•    Train less experienced technicians.
•    Monitor and report process improvements.  Review and revise technical SOPs and forms.
•    Review documentation of functions performed as part of quality control requirements. 
•    Perform all other related duties as assigned.

About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.  Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2018.


Equal Employment Opportunity 


Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet


Nearest Major Market: Durham
Nearest Secondary Market: Raleigh

Job Segment: Toxicology, Biotech, Pharmaceutical, Laboratory, Science, Research