Senior Analytical Scientist

Req ID:  204961

Saffron Walden, GB, CB10 1XL

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.


Are you an analytical Scientist that wants to take their next step in Purification Sciences?


Do you have skills and experience using UPLC / HPLC /SFC / NMR in a drug discovery environment?


Have you got the desire to join a global contract research organisation that not only supports your career development but that improves health and lives?


We offer the industry's most comprehensive drug discovery service portfolio and a multidisciplinary staff of hundreds of scientists. We have the scientific excellence and technological capabilities to support our clients throughout the drug development life cycle, from target identification to IND programs. Our team takes a true collaborative approach working in partnership with clients to find and follow the optimum path to market while moving forward together to bring novel therapies to the patients who need them.


Charles River Early Discovery is seeking an experienced, innovative, and highly motivated lab-based Senior Scientist to work within our Purification Sciences team. We are based within the Small Molecule Drug Discovery division at our Saffron Walden site.

You will be working closely within a collaborative multidisciplinary environment analysing and purifying a diverse range of small molecules to advance drug discovery projects for our clients.



What You'll Be Doing


  • Deliver high quality analytical and purification data to support the progression of compounds across multiple sites.

  • Develop customised chromatographic methodologies for challenging compounds.

  • Demonstrate strategic awareness and strong scientific knowledge to help evolve department to provide future capabilities.

  • Positive role model and supervisor of junior colleagues.

  • Identify areas for improving efficiency within the team and division.


Essential Skills and Experience


  • A strong scientific and practical background in achiral and chiral automated purification services / UPLC / HPLC / SFC / NMR / Mass Spectrometry instrumentation.

  • Hands on approach to troubleshooting and maintenance of equipment. 

  • Knowledge of MassLynx, Chemstation, Chromscope and / or Trilution would be advantageous. 

  • Experience of scale up from analytical to preparative chromatography.

  • Proven track record of implementing new technologies and creative approaches to increase effectiveness, engaging support, and promoting at a division level. 

  • Enthusiastic approach to mentoring of junior team members-providing scientific input to guide purification experiments and data interpretation. 

  • Strong written and verbal communication skills.

  • BSc or higher in an analytical, chemical or related scientific field (pharmaceutical sciences, biomedical sciences etc).


What We Offer You


  • A very comprehensive benefits package from day one, including a large pension contribution, private medical for you and family members, private dental care, critical illness cover, quarterly sales bonus and more!

  • Access to great discounts via our CREDS discount scheme.

  • Global opportunities and strong career progression.

  • The chance to work on several varied projects and liaise globally and nationally with other business areas.

  • To be able make a difference to health and wellbeing of people.

  • To continue your own career growth.

  • Flexible and hybrid working.

  • Parental leave.

  • Group Life Assurance and Group Income Protection.

  • Remote GP access 24/7.

  • Well being support and initiatives.

  • Cycle to work scheme.

  • Mentoring and Sabbaticals.



About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. 


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.


At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.