Molecular Biology Supervisor

Req ID:  83256
Location: 

Ballina, IE, F26D786

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

 

We are seeking an experienced Molecular Biology Supervisor for our Biologics Division located in Ballina, Co. Mayo, Ireland

 

The main duties & responsibilities shall be:

 

  • Oversee the quality of work produced by the Molecular Biology team and ensure it is conducted in accordance with Standard Operating Procedures and the principles of GMP.
  • Ensure on-time delivery of all client projects involving,  but not limited to, bacterial cell line characterization, DNA hybridization assays, reverse transcriptase testing, lsoenzyme
  • analysis, and PCR assays. Participate in and support cross functional communication and
  • laboratory activities as necessary
  • To implement and supervise safe working methods within the team and to inform and instruct staff of these. Comply with all Health and Safety regulations and procedures.
  • Develop, co-ordinate and implement training for staff on technical aspects of new and existing assays.
  • Responsible for providing feedback on performance to analysts working on Client specific projects.
  • Be involved in preparing costings and proposals based on protocols/project plan of proposed work by clients.
  • Assist in the transfer of assays from clients to the Department, where appropriate.
  • Participate in regulatory and client audits and liaising with clients as required.
  • Assist in the generation of appropriate SOPs.
  • Assist Project Leaders in research of technical information for incoming new enquiries.
  • Responsible for compiling audit responses in conjunction with the team and the Analytical Functional Manager.
  • Responsible for supporting staff with deviations and laboratory investigation reports.
  • Raw data review.
  • Responsible for ensuring all raw data and test results including protocols, reports etc are retained and archived according to Charles River Laboratories SOP’s.
  • Responsible for preparing ‘Presentations’ and the delivery of same to the Molecular Biology team, other departments and to Clients as required.
  • Assist in Test Item Receipt (LIMS), Storage, Disposal and Decontamination.
  • Liaise with consultants and external services (e.g. subcontract laboratories) as appropriate.
  • Liaise with other departments to ensure that the laboratory areas and all equipment maintained in appropriate working conditions.
  • Responsible for purchasing new equipment and spare/replacement parts as required.
  • Responsible for maintaining stock of supplies (chemicals, consumables) needed for routine activities within the team.
  • Scheduling daily tasks for all staff and ensuring appropriate workload is not exceeded.
     
    The following are minimum requirements related to the Molecular Biology Supervisor position.
     
  • BSc. In a relevant science discipline (e.g. Molecular Biology)
  • A minimum of 3 years relevant experience in Scientific Research preferably within a GMP regulated environment (EMEA/FDA) within the Pharmaceutical, Medical Device, CRO Industry.
  • Proven track record of supervising/managing staff.
  • Experience in molecular biology techniques, especially PCR and Q-PCR and project management desirable.
  • Experience in establishment and validation of molecular biology methods is highly desirable Ability to problem solve and work on own initiative.
  • Excellent communication and organizational skills.
     

About Biologics Testing Solutions
With more than 50 years of experience and proven regulatory expertise, the Charles River Biologics group can address challenging projects for biotechnology and pharmaceutical companies worldwide. Offering a variety of services such as contamination and impurity testing, protein characterzation, bioassays, viral clearance studies and stability and lot release programs, we support clients throughout the biologic development cycle, from the establishment and characterization of cell banks through preclinical and clinical studies to marketed products. Whether clients need stand-alone services, a unique package of testing, or insourced support, our Biologics group can create a custom solution to suit their needs.  Each year more than 20,000 biologic testing reports are sent each and over 200 licenses products are supported by our biologics testing solutions team.

 

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

 

With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased to $2.67 billion. 

 

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.