Al bijna 75 jaar werken de medewerkers van Charles River samen om te helpen bij het ontdekken, ontwikkelen en veilig maken van nieuwe geneesmiddelen. Wanneer u bij onze familie komt, heeft u een belangrijke impact op de gezondheid en het welzijn van mensen over de hele wereld. Of uw achtergrond in levenswetenschappen, financiën, IT, verkoop of een ander gebied is, uw vaardigheden spelen een belangrijke rol in het werk dat we uitvoeren. In ruil hiervoor helpen wij u een carrière op te bouwen waar u over gepassioneerd kunt voelen.
Do you want to start your career at an international renowned organisation within the life science industry?
Then come to us for an internship or graduation project. This will give you the opportunity to gain experience and develop skills that will boost your career.
This is your moment!
Intern Discovery and Environmental sciences department
Department:
The Discovery & Environmental Sciences department consists of approximately 90 employees. Within this department, research is carried out to investigate the safety of existing and new substances. The work is characterized by a great diversity of tests, test substances, customers, collaborations and innovation.
About our team:
The department consists of four sections: In-vitro and genetic toxicology, in-vitro drug metabolism and pharmacokinetics, ecotoxicology, and the innovation team.
The in-vitro sections perform research with primary cells, cell cultures, 3D tissue models or other types of test systems, and investigate effect of substances (drugs, pesticides, chemicals) on genetic toxicity endpoints like mutations or chromosome damage, endocrine disruption properties, skin and eye toxicity or other types of toxicity. Also, absorption, binding and metabolism of substances is investigated. Several different techniques are used, such as cell culturing, flow cytometry, high-content analysis, PCR and analytical techniques like HPLC, LC-MS, luminescence or fluorescence.
The ecotoxicology group investigates effects of substances on the aqueous environment by performing studies with algae, daphnia, midge, fish, and amphibians.
Internship project: Development of Oligonucleotide Analysis using Mass Spectrometry
We are seeking a student experienced in mass spectrometry, preferably high-resolution mass spectrometry, to contribute to the advancement of oligonucleotide analysis across various biological matrices. This includes liver cells, different cell fractions, and plasma. The project involves comparing several sample preparation methods, mass spectrometry/HPLC methods, and data analysis approaches. You will start with commercial standards. After a mass spectrometry/HPLC method has been developed, pilots with biological matrices can be initiated. Initial method development has already been conducted, which can serve as a foundation for further exploration. You will have access to state-of-the-art equipment such as a new Orbitrap Exploris 480. You will also work closely together with other lab technicians to ensure the methods are within industry standards.
You will be working at the in vitro ADME (absorption, distribution, metabolism, and excretion) group. Our group specialized in profiling the metabolism of small and large molecules in several matrices. We furthermore continuously develop methods and strategies to analyse novel molecules.
What is required?
• Third year Bachelor HBO or Master student in analytical chemistry;
• You are enthusiastic about analytical characterization techniques;
• You are trained to work safely and effectively in a laboratory environment;
• You have experience with HPLC analysis and knowledge about high-resolution mass spectrometry;
• Proactive teamplayer, strong analytical skills, capable of critically evaluating data;
• You are searching for an internship where you have the freedom to take initiative;
• You are available for a period of at least 4 – 6 months for 5 days a week.
Selection procedure:
• After receiving your application, we need some time to review. After the review we will inform you if you will be invited for an interview.
• During the interview we will discuss the subject of the internship.
• If the internship is assigned to you, our HR colleagues will take care of your internship agreement.
Our offer to you:
Interning at Charles River means working in state-of-the-art laboratory. On-the-job training under the guidance of a senior analyst and the opportunity to develop and grow in your field.
• The chance to gain experience in your field of study;
• An opportunity to maximize your potential and possibilities for your first job after graduation;
• Monthly internship allowance.
Over Safety Assessment
Charles River helpt zijn partners bij het versneld uitvoeren van preklinische geneesmiddelontwikkeling dankzij uitstekende programma’s voor veiligheidsbeoordeling, de allernieuwste voorzieningen en deskundig advies op het gebied van wet- en regelgeving. Van individuele gespecialiseerde toxicologie- en “IND enabling”-onderzoeken tot pakketten op maat en complete laboratoriumondersteuning: ons ervaren team kan programma’s ontwerpen en uitvoeren die anticiperen op problemen en obstakels uit de weg gaan, voor een probleemloze en efficiënte ontwikkelingsgang naar de markt. Bij onze Safety Assessment-vestigingen lopen jaarlijks zo’n 300 programma’s voor experimentele nieuwe geneesmiddelen (investigational new drugs [IND’s]).
Over Charles River
Charles River is een organisatie die op contract onderzoek naar vroege fasen verricht (CRO). Wij hebben op ons fundament van proefdieren, geneeskunde en wetenschap voortgebouwd om een brede portefeuille van discovery- en veiligheidsbeoordelingsdiensten te ontwikkelen (zowel Good Laboratory Practice (GLP) als non-GLP) en onze cliënten te helpen, van de inventarisatie van targets tot preklinische ontwikkeling. Charles River levert tevens een verzameling producten en diensten die tegemoetkomen aan de behoeften van onze cliënten op het gebied van klinisch laboratoriumonderzoek en productieactiviteiten. Dankzij deze brede portefeuille van producten en diensten kunnen onze cliënten een flexibeler model voor geneesmiddelontwikkeling creëren, wat de kosten verlaagt en de productiviteit en effectiviteit verhoogt zodat producten eerder op de markt gebracht kunnen worden.
Met meer dan 20.000 medewerkers bij 110 vestigingen in 20 landen wereldwijd zijn wij strategisch gepositioneerd voor het coördineren van wereldwijde middelen en kunnen wij multidisciplinaire inzichten inzetten om de unieke uitdagingen van onze cliënten op te lossen. Onze cliënten omvatten farmaceutische multinationals, biotechnologiebedrijven, overheidsinstellingen en medische en universitaire instellingen over de gehele wereld.
Bij Charles River zijn wij gepassioneerd over onze rol bij de verbetering van de levenskwaliteit van andere mensen. Onze missie, onze uitstekende wetenschap en onze doelgerichte instelling werken door in alles wat we doen, en we gaan elke dag opnieuw aan de slag met de kennis dat ons werk de gezondheid en het welzijn van vele mensen helpt te verbeteren. Wij zijn trots te kunnen zeggen dat wij een rol hebben gespeeld bij de ontwikkeling van circa 86% van de geneesmiddelen die in 2021 door de Amerikaanse FDA werden goedgekeurd.
Meer informatie vindt u op www.criver.com.
Helping you find your moment
You take great care and effort when you apply for a job with us. Rest assured that we’ll be just as diligent in finding the role that’s right for you. Here’s how our hiring process works:
Job Search
Learn about CRL, our culture, and why we do the work we do while also searching for roles that match your interests and expertise.
Application
Create a profile and apply to as many roles as you have an interest.
Note: Depending on the role, you may be required to include a resume in your application.
Assessment and application review
Complete assessments, if requested, to determine whether the role is likely to be a good fit for you – and vice versa. The recruiter will review your resume and qualifications against the requirements of the role and will determine next steps.
Note: At any point in the process, you can log into your profile to review the status of your application.
Interview
Engage in our interview process by meeting with a group of interviewers who will provide information on the company, culture, and your role while also asking you questions to assess your skills, interests, and expertise. This is also a great time for you to ask questions and better understand how we foster a sense of belonging at Charles River.
Note: Charles River leverages technical and behavioral-based interview questions based on our DNA (Care, Lead, Own, and Collaborate). Please familiarize yourself with the DNA and be prepared to relate your experiences to them.
Job offer and onboarding
Receive a competitive offer either by phone or email from a Charles River recruiter or hiring manager. The offer will include your title, salary, location, and other relevant information.
Note: Upon acceptance, you will work with your recruiter to confirm a start date and will receive paperwork to electronically complete prior to your start. For US-based roles, upon your acceptance, you will be required to take a pre-employment drug screen and pass a criminal background check.
Job Search
Learn about CRL, our culture, and why we do the work we do while also searching for roles that match your interests and expertise.
Application
Create a profile and apply to as many roles as you have an interest. Note: Depending on the role, you may be required to include a resume in your application.
Assessment and Application Review
Complete assessments, if requested, to determine whether the role is likely to be a good fit for you – and vice versa. The recruiter will review your resume and qualifications against the requirements of the role and will determine next steps.
Note: At any point in the process, you can log into your profile to review the status of your application.
Interview
Engage in our interview process by meeting with a group of interviewers who will provide information on the company, culture, and your role while also asking you questions to assess your skills, interests, and expertise. This is also a great time for you to ask questions and better understand how we foster a sense of belonging at Charles River. Note: Charles River leverages technical and behavioral-based interview questions based on our DNA (Care, Lead, Own, and Collaborate). Please familiarize yourself with the DNA and be prepared to relate your experiences to them.
Job offer and onboarding
Receive a competitive offer either by phone or email from a Charles River recruiter or hiring manager. The offer will include your title, salary, location, and other relevant information. Note: Upon acceptance, you will work with your recruiter to confirm a start date and will receive paperwork to electronically complete prior to your start. For US-based roles, upon your acceptance, you will be required to take a pre-employment drug screen and pass a criminal background check.
Featured jobs
Important things are happening every moment at Charles River. This means exciting new career opportunities for you to explore. Take a look and apply today!
Looking for something else? Search all jobs.
Moment by moment
At Charles River, you’ll be able to contribute to incredible breakthroughs while experiencing exciting opportunities for growth and development.
-
UX/UI Designer
Advocate for user-centered design solutions. Create distinctive, consistent, branded digital experiences across multiple platforms, devices, and channels.
-
Sr. UX/UI Designer
Define and drive UX/UI strategies and interaction designs – from scratch and for scale – that solve business and user problems.
-
Associate Director
Work with Sr. UX/IX Designers and developers to assess problems and develop solutions. Execute on plan by building coding standardisations and automating processes.
-
Director, Digital Data Enablement
Lead UX management and operational teams across business units and technical teams. Identify and define fit-for-purpose strategies to integrate best practices.
-
Sr. Director UX/UI Design
Mentor, coach, and guide designer teams on design strategy related to research insights, execution, continuous integration, and automated deployment.
-
-
Animal Care Technician I-IV
Maintain the well-being of our animals by providing food, water, and a clean environment.
-
Animal Care Technologist I-IV
Provide specialised care to maintain and monitor our animal's health and physical environment.
-
Veterinary Technician
Help monitor, document, and triage all laboratory animal health cases.
-
Team Leader / Supervisor
Supervise, train, mobilise, empower, and develop a high-performing team.
-
Research Associate
Coordinate and plan activities according to study plan guidelines.
-
-
Intern Level I
Support process/procedure improvement based on site and department needs. Gain knowledge of our corporate environment to navigate cross-functional department collaboration.
-
Intern Level II
Complete comprehensive departmental projects incorporating mentorship of Level I interns as a professional development component.
-
Biomanufacturing Technician I-III
Oversee the production, formulation, and banking of cellular products while maintaining compliance with GMP, GDP, and aseptic guidelines.
-
Biomanufacturing Lead / Specialist
Maintain in-depth knowledge of specialised equipment to address questions as a Subject Matter Expert for the required equipment.
-
-
Clinical Veterinarian I-III
Responsible for delivering professional veterinary services and helping to manage all phases of health care for the animal colony.
-
Senior Clinical Veterinarian
Utlise knowledge of laboratory animal medicine to optimise the scientific objectives of animal research protocols.
-
Principal Veterinarian / Associate Director
Conduct veterinary consultations, make treatment recommendations, communicate with study directors, and follow cases through to resolution.
-
Director, Laboratory Animal Medicine
Provide technical and professional oversight of all animal care and use functions involving site laboratory animals.
-
-
Technician I-III
Follow SOP and protocols in the areas of animal handling, husbandry, and blood/urine collection.
-
Technician IV-V
Handle advanced technician duties, including anesthesia, leadership and specialised sample collections.
-
Project Leader (Scientific)
Serve as a scientific expert for the Lab with responsibility for staff-conducted studies.
-
Team Leader (People Leader)
Oversee team activities and gain leadership skills on the path to becoming a Team Supervisor.
-
Team Supervisor (People Leader)
Responsible for overall employee supervision, staff development, and team success.
-
-
Financial Analyst
Help analyse financial data, extract/define relevant information, and interpret data.
-
Financial Analyst II
Responsible for analysis, forecasting, budgeting, accounting administration, and reporting of projects.
-
Senior Financial Analyst
Handle weekly and monthly forecasting and annual budget preparation. Prepare financials and key indicators for business reviews.
-
Manager, Business Finance
Partner with operating businesses to raise standards in key decision areas. Present a dynamic industry, competitor, and economic context.
-
Finance Director, Operation
Support all business aspects, working with site teams to direct weekly/monthly forecasting and annual budget preparation.
-
-
Biomanufacturing Technician I
Support the production, formulation, and banking of novel cellular products (including cGMP, GDP, and aseptic processing).
-
Biomanufacturing Technician II
Perform specialised activities in the production, formulation, and banking of novel cellular products (including cGMP, GDP, and aseptic processing). Train Biomanufacturing Technician 1.
-
Biomanufacturing Technician III
Help advance the production, formulation, and banking of novel cellular products (including cGMP, GDP, and aseptic processing) while interacting with clients.
-
Biomanufacturing Lead / Specialist
Maintain in-depth knowledge of specialised equipment to address questions as a Subject Matter Expert for the required equipment.
-
Biomanufacturing Supervisor
Oversee biomanufacturing personnel, ensuring compliance with cGMP’s, CRL quality systems, and process documents in biomanufacturing.
-
Biomanufacturing Manager
Lead biomanufacturing activities in the start-up and cGMP production of novel cellular products. Schedule and manage staff, ensuring a safe and compliant working environment.
-
-
Client Manager
Ensures high-quality customer service through multi-site coordination. Deliver timely, accurate, and comprehensive responses to sponsor requests.
-
Business Development Director
Deliver profitable sales growth by targeting and visiting clients to build strong relationships and customer loyalty.
-
Senior Business Development Director
Plan and execute a territory-based field sales strategy. Drive growth through targeted long- and short-term account plans.
-
Regional Sales Manager
Manage sales team within North America's Safety Assessment sales region to achieve sales and profit goals.
-
-
Director
Partner with site leadership to achieve performance goals, develop staff, and deliver succession planning.
-
Senior Director / General Manager
Lead a multi-functional team to ensure integrated operations. Collaborate with senior leadership to form plans, objectives, and policies.
-
Executive Director
Lead a global, mutidisciplinary team. Develop short and long-term strategic plans tp maximise growth and profitability.
-
Corporate Vice President
Provide leadership, direction, and advice to leadership and finance teams. Accountable for financial planning, directing, and controlling.
-
About Charles River
Charles River is an early-stage Contract Research Organisation (CRO). Here, we are passionate about our role in improving the quality of people’s lives. With 100 sites around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our clients’ unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies, hospitals, and academic institutions around the world.
Supporting your well-being
Your dedication and passion make a life-saving difference in lives around the world. We’re committed to providing you with benefits that elevate your quality of life.
Financial
- Earnings + incentives
- Retirement benefits
- Holidays + time away
- Recognition
- Employee Assistance
Career
- Professional development opportunities
- Career development
- Awards
- Educational support
Health & wellness provision
- Employee well-being support
- Family Support Assistance
- Parental benefits + family formation benefits
- Work-life balance flexibility
Social and Community
- Culture of inclusion
- 11 employee resource groups (ERGs) with >3,000 members
- Opportunities for paid volunteer time off
- Community outreach + matching gift + engagement activities
About Charles River
Charles River is an early-stage Contract Research Organisation (CRO). Here, we are passionate about our role in improving the quality of people’s lives. With 100 sites around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our clients’ unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies, hospitals, and academic institutions around the world.